Pseudomonas aeruginosa RP73, M062_02320

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF47384
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF47384
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00304
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG prp02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 257 316 8.76927E-12
CDD cd18773 PDC1_HK_sensor - - 40 167 2.52542E-4
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 318 473 2.9E-25
SMART SM00388 HisKA_10 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 255 320 3.4E-16
Gene3D G3DSA:6.10.340.10 - - - 168 255 2.2E-9
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 258 319 1.3E-12
Gene3D G3DSA:3.30.450.20 PAS domain - - 68 167 1.7E-7
PANTHER PTHR45436 SENSOR HISTIDINE KINASE YKOH - - 2 473 6.9E-75
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 310 473 7.86E-29
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 365 474 3.0E-16
SMART SM00304 HAMP_11 IPR003660 HAMP domain 204 255 3.5E-5
Coils Coil Coil - - 301 321 -
Gene3D G3DSA:1.10.287.130 - - - 256 317 3.6E-13
CDD cd06225 HAMP - - 210 250 3.53447E-5
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 241 319 2.75E-13
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 369 468 1.3E-10
Pfam PF00672 HAMP domain IPR003660 HAMP domain 201 251 1.5E-7
CDD cd16945 HATPase_CreC-like - - 366 471 4.64596E-59
SUPERFAMILY SSF103190 Sensory domain-like IPR029151 Periplasmic sensor-like domain superfamily 79 179 2.86E-12

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.