Pseudomonas aeruginosa RP73, M062_02500

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SFLDS00029
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051536 iron-sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SFLDS00029
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009102 biotin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01694
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004076 biotin synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01694
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other RP73 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG prp00780 Biotin metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG prp01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc biotin biosynthesis from 8-amino-7-oxononanoate II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd01335 Radical_SAM - - 56 255 1.10731E-15
Hamap MF_01694 Biotin synthase [bioB]. IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB 11 319 41.772034
Pfam PF06968 Biotin and Thiamin Synthesis associated domain IPR010722 Biotin and thiamin synthesis-associated domain 226 316 1.1E-20
PANTHER PTHR22976 BIOTIN SYNTHASE IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB 5 333 0.0
SFLD SFLDF00272 biotin synthase IPR024177 Biotin synthase 4 325 0.0
SFLD SFLDS00029 Radical SAM IPR007197 Radical SAM 4 325 0.0
SMART SM00729 MiaB IPR006638 Elp3/MiaA/NifB-like, radical SAM core domain 49 261 3.6E-39
NCBIfam TIGR00433 JCVI: biotin synthase BioB IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB 12 316 1.4E-125
Pfam PF04055 Radical SAM superfamily IPR007197 Radical SAM 56 208 7.0E-14
SMART SM00876 BATS_2 IPR010722 Biotin and thiamin synthesis-associated domain 226 318 3.6E-48
PIRSF PIRSF001619 Biotin_synth IPR024177 Biotin synthase 1 325 0.0
SUPERFAMILY SSF102114 Radical SAM enzymes - - 11 320 2.09E-92
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 10 321 0.0
FunFam G3DSA:3.20.20.70:FF:000011 Biotin synthase - - 10 321 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.