Pseudomonas aeruginosa RP73, M062_18570 (metG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004825 methionine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00098
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006431 methionyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00399
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF09334
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00399
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006418 tRNA aminoacylation for protein translation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF09334
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000049 tRNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01588
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00399
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Translation, post-translational modification, degradation Other RP73 genes in this class
Amino acid biosynthesis and metabolism Other RP73 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG prp00450 Selenocompound metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG prp00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF47323 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding 389 547 8.97E-43
NCBIfam TIGR00399 JCVI: methionine--tRNA ligase subunit beta IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal 543 677 7.7E-40
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 250 261 2.2E-24
FunFam G3DSA:2.40.50.140:FF:000042 Methionine--tRNA ligase - - 567 677 8.6E-43
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 89 100 2.2E-24
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 383 394 2.2E-24
SUPERFAMILY SSF50249 Nucleic acid-binding proteins IPR012340 Nucleic acid-binding, OB-fold 570 676 1.64E-26
Pfam PF09334 tRNA synthetases class I (M) IPR015413 Methionyl/Leucyl tRNA synthetase 7 395 0.0
PANTHER PTHR45765 METHIONINE--TRNA LIGASE IPR023458 Methionine-tRNA ligase, type 1 3 675 0.0
NCBIfam TIGR00398 JCVI: methionine--tRNA ligase IPR014758 Methionyl-tRNA synthetase 7 535 0.0
FunFam G3DSA:1.10.730.10:FF:000005 Methionine--tRNA ligase - - 388 526 2.3E-57
CDD cd00814 MetRS_core IPR033911 Methioninyl-tRNA synthetase core domain 6 370 0.0
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 7 383 0.0
CDD cd02800 tRNA_bind_EcMetRS_like IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal 571 677 1.90229E-42
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 9 22 2.2E-24
FunFam G3DSA:2.20.28.20:FF:000001 Methionine--tRNA ligase - - 141 175 8.8E-16
Pfam PF19303 Anticodon binding domain of methionyl tRNA ligase IPR041872 Methionyl-tRNA synthetase, anticodon-binding domain 416 517 3.4E-7
Pfam PF01588 Putative tRNA binding domain IPR002547 tRNA-binding domain 581 674 3.6E-20
CDD cd07957 Anticodon_Ia_Met IPR041872 Methionyl-tRNA synthetase, anticodon-binding domain 373 505 6.16266E-37
Hamap MF_00098 Methionine--tRNA ligase [metG]. IPR023458 Methionine-tRNA ligase, type 1 5 545 39.35619
Gene3D G3DSA:2.20.28.20 - IPR029038 Methionyl-tRNA synthetase, Zn-domain 141 175 0.0
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 41 55 2.2E-24
SUPERFAMILY SSF57770 Methionyl-tRNA synthetase (MetRS), Zn-domain IPR029038 Methionyl-tRNA synthetase, Zn-domain 141 175 5.36E-12
SUPERFAMILY SSF52374 Nucleotidylyl transferase - - 4 386 1.13E-98
PRINTS PR01041 Methionyl-tRNA synthetase signature IPR033911 Methioninyl-tRNA synthetase core domain 290 305 2.2E-24
Gene3D G3DSA:2.40.50.140 - IPR012340 Nucleic acid-binding, OB-fold 568 677 1.3E-32
Gene3D G3DSA:1.10.730.10 - - - 388 526 1.6E-36

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.