Pseudomonas aeruginosa RP73, M062_18930

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0051051 negative regulation of transport
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA3574
 ECO:0000249
sequence similarity evidence used in automatic assertion		 15855496
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00440
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transcriptional regulators Other RP73 genes in this class
Antibiotic resistance and susceptibility Other RP73 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG prp01501 beta-Lactam resistance 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00455 TetR bacterial regulatory protein HTH signature IPR001647 DNA-binding HTH domain, TetR-type 15 28 6.8E-12
PRINTS PR00455 TetR bacterial regulatory protein HTH signature IPR001647 DNA-binding HTH domain, TetR-type 36 59 6.8E-12
FunFam G3DSA:1.10.10.60:FF:000141 TetR family transcriptional regulator - - 8 59 3.8E-15
Gene3D G3DSA:1.10.357.10 Tetracycline Repressor, domain 2 - - 1 212 1.4E-97
SUPERFAMILY SSF46689 Homeodomain-like IPR009057 Homeobox-like domain superfamily 1 65 7.98E-19
PANTHER PTHR30055 HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR - - 2 206 1.4E-25
FunFam G3DSA:1.10.357.10:FF:000003 HTH-type transcriptional regulator AcrR - - 1 212 1.7E-83
SUPERFAMILY SSF48498 Tetracyclin repressor-like, C-terminal domain IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily 83 202 8.01E-12
Pfam PF08361 MAATS-type transcriptional repressor, C-terminal region IPR013572 Transcription regulator MAATS, C-terminal 83 198 2.0E-13
Pfam PF00440 Bacterial regulatory proteins, tetR family IPR001647 DNA-binding HTH domain, TetR-type 15 61 7.9E-18

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.