Pseudomonas entomophila L48, PSEEN4945 (mutL)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0016887	ATPase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR10073	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005524	ATP binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF08676	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0140664	ATP-dependent DNA damage sensor activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR10073	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0030983	mismatched DNA binding	ISM Inferred from Sequence Model Term mapped from: InterPro:SM01340	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Cellular Component	GO:0032300	mismatch repair complex	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR10073	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006298	mismatch repair	ISM Inferred from Sequence Model Term mapped from: InterPro:PF08676	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pen03430	Mismatch repair	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Pfam	PF13589	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	29	124	1.6E-9
SUPERFAMILY	SSF54211	Ribosomal protein S5 domain 2-like	IPR020568	Ribosomal protein uS5 domain 2-type superfamily	195	334	7.59E-40
Gene3D	G3DSA:3.30.1540.20	-	IPR042120	MutL, C-terminal domain, dimerisation subdomain	448	625	3.2E-59
CDD	cd16926	HATPase_MutL-MLH-PMS-like	-	-	14	201	1.85326E-108
Hamap	MF_00149	DNA mismatch repair protein MutL [mutL].	IPR020667	DNA mismatch repair protein, MutL	5	628	29.605238
CDD	cd03482	MutL_Trans_MutL	-	-	212	334	2.46985E-70
FunFam	G3DSA:3.30.565.10:FF:000003	DNA mismatch repair endonuclease MutL	-	-	5	216	6.3E-82
FunFam	G3DSA:3.30.1370.100:FF:000005	DNA mismatch repair protein MutL	-	-	488	583	1.2E-48
PANTHER	PTHR10073	DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL	IPR038973	DNA mismatch repair protein MutL/Mlh/Pms-like	447	618	2.1E-123
NCBIfam	TIGR00585	JCVI: DNA mismatch repair endonuclease MutL	IPR002099	DNA mismatch repair protein MutL/Mlh/PMS	7	557	0.0
Pfam	PF08676	MutL C terminal dimerisation domain	IPR014790	MutL, C-terminal, dimerisation	441	588	3.5E-51
MobiDBLite	mobidb-lite	consensus disorder prediction	-	-	378	397	-
MobiDBLite	mobidb-lite	consensus disorder prediction	-	-	376	397	-
FunFam	G3DSA:3.30.230.10:FF:000013	DNA mismatch repair endonuclease MutL	-	-	221	332	4.8E-52
SUPERFAMILY	SSF55874	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	6	208	1.7E-53
SMART	SM01340	DNA_mis_repair_2	IPR013507	DNA mismatch repair protein, S5 domain 2-like	216	334	1.5E-61
Gene3D	G3DSA:3.30.565.10	-	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	6	220	1.4E-69
SMART	SM00853	MutL_C_2	IPR014790	MutL, C-terminal, dimerisation	445	588	2.9E-55
Pfam	PF01119	DNA mismatch repair protein, C-terminal domain	IPR013507	DNA mismatch repair protein, S5 domain 2-like	218	333	1.5E-38
Gene3D	G3DSA:3.30.230.10	-	IPR014721	Small ribosomal subunit protein uS5 domain 2-type fold, subgroup	221	331	1.5E-31
Gene3D	G3DSA:3.30.1370.100	-	IPR042121	MutL, C-terminal domain, regulatory subdomain	488	583	3.2E-59
SUPERFAMILY	SSF118116	DNA mismatch repair protein MutL	IPR037198	MutL, C-terminal domain superfamily	441	630	9.15E-61

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.