Pseudomonas stutzeri DSM 4166, PSTAA_3763 (mutL)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Cellular Component	GO:0032300	mismatch repair complex	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR10073	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006298	mismatch repair	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00585	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005524	ATP binding	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00585	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0030983	mismatched DNA binding	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00585	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0140664	ATP-dependent DNA damage sensor activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR10073	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016887	ATPase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR10073	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	psr03430	Mismatch repair	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
NCBIfam	TIGR00585	JCVI: DNA mismatch repair endonuclease MutL	IPR002099	DNA mismatch repair protein MutL/Mlh/PMS	7	550	0.0
Hamap	MF_00149	DNA mismatch repair protein MutL [mutL].	IPR020667	DNA mismatch repair protein, MutL	5	621	30.196287
CDD	cd03482	MutL_Trans_MutL	-	-	212	333	7.46502E-73
FunFam	G3DSA:3.30.1370.100:FF:000005	DNA mismatch repair protein MutL	-	-	481	576	2.5E-49
Pfam	PF01119	DNA mismatch repair protein, C-terminal domain	IPR013507	DNA mismatch repair protein, S5 domain 2-like	217	333	2.3E-40
SUPERFAMILY	SSF118116	DNA mismatch repair protein MutL	IPR037198	MutL, C-terminal domain superfamily	434	623	1.01E-63
Pfam	PF08676	MutL C terminal dimerisation domain	IPR014790	MutL, C-terminal, dimerisation	434	581	5.4E-52
Gene3D	G3DSA:3.30.565.10	-	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	6	220	1.5E-72
SMART	SM00853	MutL_C_2	IPR014790	MutL, C-terminal, dimerisation	438	581	2.8E-57
Gene3D	G3DSA:3.30.1370.100	-	IPR042121	MutL, C-terminal domain, regulatory subdomain	481	576	1.7E-60
SMART	SM01340	DNA_mis_repair_2	IPR013507	DNA mismatch repair protein, S5 domain 2-like	216	334	2.9E-63
SUPERFAMILY	SSF54211	Ribosomal protein S5 domain 2-like	IPR020568	Ribosomal protein uS5 domain 2-type superfamily	195	334	6.83E-41
Pfam	PF13589	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	28	130	5.0E-10
Gene3D	G3DSA:3.30.1540.20	-	IPR042120	MutL, C-terminal domain, dimerisation subdomain	441	618	1.7E-60
FunFam	G3DSA:3.30.565.10:FF:000003	DNA mismatch repair endonuclease MutL	-	-	5	217	5.0E-84
SUPERFAMILY	SSF55874	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	5	208	3.8E-56
CDD	cd16926	HATPase_MutL-MLH-PMS-like	-	-	14	201	1.53522E-110
PANTHER	PTHR10073	DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL	IPR038973	DNA mismatch repair protein MutL/Mlh/Pms-like	439	612	2.1E-129
Gene3D	G3DSA:3.30.230.10	-	IPR014721	Small ribosomal subunit protein uS5 domain 2-type fold, subgroup	221	331	6.1E-32
FunFam	G3DSA:3.30.230.10:FF:000013	DNA mismatch repair endonuclease MutL	-	-	221	332	3.1E-55

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.