Pseudomonas stutzeri DSM 10701, PSJM300_06755 (fadB)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Biological Process | GO:0009062 | fatty acid catabolic process |
Inferred from Sequence Model
Term mapped from: InterPro:MF_01621
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0004300 | enoyl-CoA hydratase activity |
Inferred from Sequence Model
Term mapped from: InterPro:MF_01621
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity |
Inferred from Sequence Model
Term mapped from: InterPro:MF_01621
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0006631 | fatty acid metabolic process |
Inferred from Sequence Model
Term mapped from: InterPro:PF00725
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0008692 | 3-hydroxybutyryl-CoA epimerase activity |
Inferred from Sequence Model
Term mapped from: InterPro:MF_01621
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
Inferred from Sequence Model
Term mapped from: InterPro:PF00725
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0070403 | NAD+ binding |
Inferred from Sequence Model
Term mapped from: InterPro:PF02737
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0016491 | oxidoreductase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PF00725
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0004165 | dodecenoyl-CoA delta-isomerase activity |
Inferred from Sequence Model
Term mapped from: InterPro:MF_01621
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Cellular Component | GO:0036125 | fatty acid beta-oxidation multienzyme complex |
Inferred from Sequence Model
Term mapped from: InterPro:MF_01621
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
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|
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | psj01130 | Biosynthesis of antibiotics | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | jasmonic acid biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | androstenedione degradation | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | pyruvate fermentation to hexanol (engineered) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | psj01212 | Fatty acid metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | psj01120 | Microbial metabolism in diverse environments | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | 3-hydroxypropanoate/4-hydroxybutanate cycle | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | glutaryl-CoA degradation | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | psj00071 | Fatty acid degradation | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | fermentation to 2-methylbutanoate | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | (R)- and (S)-3-hydroxybutanoate biosynthesis (engineered) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | unsaturated, even numbered fatty acid β-oxidation | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | psj00650 | Butanoate metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | oleate β-oxidation (reductase-dependent, yeast) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | <i>Spodoptera littoralis</i> pheromone biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | psj00410 | beta-Alanine metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | oleate β-oxidation (isomerase-dependent, yeast) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | 10-<i>cis</i>-heptadecenoyl-CoA degradation (yeast) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | psj00380 | Tryptophan metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | oleate β-oxidation (thioesterase-dependent, yeast) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | 4-coumarate degradation (anaerobic) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | psj00310 | Lysine degradation | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | psj00362 | Benzoate degradation | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | 10-<i>trans</i>-heptadecenoyl-CoA degradation (reductase-dependent, yeast) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | psj00903 | Limonene and pinene degradation | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | cholesterol degradation to androstenedione II (cholesterol dehydrogenase) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | psj00640 | Propanoate metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | psj00930 | Caprolactam degradation | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | 4-hydroxybenzoate biosynthesis III (plants) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | pyruvate fermentation to butanol I | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | cholesterol degradation to androstenedione I (cholesterol oxidase) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | methyl <i>tert</i>-butyl ether degradation | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | benzoyl-CoA degradation I (aerobic) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | psj00281 | Geraniol degradation | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | psj01040 | Biosynthesis of unsaturated fatty acids | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | fatty acid β-oxidation III (unsaturated, odd number) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | (8<i>E</i>,10<i>E</i>)-dodeca-8,10-dienol biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | 2-methylpropene degradation | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | 9-<i>cis</i>, 11-<i>trans</i>-octadecadienoyl-CoA degradation (isomerase-dependent, yeast) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | crotonate fermentation (to acetate and cyclohexane carboxylate) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | docosahexaenoate biosynthesis III (6-desaturase, mammals) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | psj01100 | Metabolic pathways | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | psj01200 | Carbon metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | pyruvate fermentation to butanol II (engineered) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | psj01110 | Biosynthesis of secondary metabolites | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | fatty acid β-oxidation II (peroxisome) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | psj00280 | Valine, leucine and isoleucine degradation | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | methyl ketone biosynthesis (engineered) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | fatty acid salvage | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | 4-coumarate degradation (aerobic) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Pfam | PF00725 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain | IPR006108 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal | 497 | 592 | 2.5E-23 |
| Pfam | PF02737 | 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain | IPR006176 | 3-hydroxyacyl-CoA dehydrogenase, NAD binding | 317 | 495 | 1.9E-62 |
| FunFam | G3DSA:3.40.50.720:FF:000009 | Fatty oxidation complex, alpha subunit | - | - | 314 | 499 | 7.3E-74 |
| Gene3D | G3DSA:3.90.226.10 | - | - | - | 1 | 313 | 8.8E-119 |
| SUPERFAMILY | SSF52096 | ClpP/crotonase | IPR029045 | ClpP/crotonase-like domain superfamily | 2 | 306 | 2.65E-64 |
| NCBIfam | TIGR02437 | JCVI: fatty acid oxidation complex subunit alpha FadB | IPR012799 | Fatty oxidation complex, alpha subunit FadB | 1 | 714 | 0.0 |
| SUPERFAMILY | SSF48179 | 6-phosphogluconate dehydrogenase C-terminal domain-like | IPR008927 | 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily | 496 | 612 | 1.28E-28 |
| Gene3D | G3DSA:1.10.1040.50 | - | - | - | 500 | 709 | 4.3E-70 |
| Gene3D | G3DSA:3.40.50.720 | - | - | - | 314 | 499 | 2.2E-68 |
| PANTHER | PTHR43612 | TRIFUNCTIONAL ENZYME SUBUNIT ALPHA | - | - | 4 | 714 | 0.0 |
| FunFam | G3DSA:1.10.1040.50:FF:000001 | Fatty acid oxidation complex subunit alpha | - | - | 500 | 714 | 1.2E-115 |
| CDD | cd06558 | crotonase-like | - | - | 16 | 204 | 2.92995E-53 |
| Pfam | PF00378 | Enoyl-CoA hydratase/isomerase | IPR001753 | Enoyl-CoA hydratase/isomerase | 15 | 208 | 2.0E-37 |
| FunFam | G3DSA:3.90.226.10:FF:000018 | Fatty acid oxidation complex subunit alpha | - | - | 1 | 313 | 0.0 |
| SUPERFAMILY | SSF48179 | 6-phosphogluconate dehydrogenase C-terminal domain-like | IPR008927 | 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily | 623 | 714 | 5.7E-23 |
| SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | IPR036291 | NAD(P)-binding domain superfamily | 315 | 496 | 9.05E-58 |
| Hamap | MF_01621 | Fatty acid oxidation complex subunit alpha [fadB]. | IPR012799 | Fatty oxidation complex, alpha subunit FadB | 1 | 715 | 52.267578 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.