Pseudomonas stutzeri RCH2, Psest_4225

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd02888
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd02888
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0031419 cobalamin binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd02888
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc adenosine deoxyribonucleotides <i>de novo</i> biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG psh01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc guanosine deoxyribonucleotides <i>de novo</i> biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG psh00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc adenosine deoxyribonucleotides <i>de novo</i> biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides biosynthesis from CTP InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc guanosine deoxyribonucleotides <i>de novo</i> biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides <i>de novo</i> biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides <i>de novo</i> biosynthesis IV InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc pyrimidine deoxyribonucleotides <i>de novo</i> biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG psh00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 317 328 1.0E-17
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 393 415 1.0E-17
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 509 536 1.0E-17
SUPERFAMILY SSF51998 PFL-like glycyl radical enzymes - - 14 689 0.0
CDD cd02888 RNR_II_dimer IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent 69 652 0.0
Pfam PF02867 Ribonucleotide reductase, barrel domain IPR000788 Ribonucleotide reductase large subunit, C-terminal 104 650 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 421 444 1.0E-17
NCBIfam TIGR02504 JCVI: adenosylcobalamin-dependent ribonucleoside-diphosphate reductase IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent 25 659 0.0
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 355 378 1.0E-17
PRINTS PR01183 Ribonucleotide reductase large chain signature IPR000788 Ribonucleotide reductase large subunit, C-terminal 178 197 1.0E-17
PANTHER PTHR43371 VITAMIN B12-DEPENDENT RIBONUCLEOTIDE REDUCTASE - - 18 710 0.0
Gene3D G3DSA:3.20.70.20 - - - 9 653 0.0
FunFam G3DSA:3.20.70.20:FF:000040 Vitamin B12-dependent ribonucleotide reductase - - 1 653 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.