Pseudomonas mendocina NK-01, MDS_0004

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00986
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006265 DNA topological change
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00986
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005694 chromosome
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01059
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00986
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00986
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 7 219 9.17E-75
PRINTS PR00418 DNA topoisomerase II family signature - - 37 52 2.5E-71
PRINTS PR00418 DNA topoisomerase II family signature - - 115 129 2.5E-71
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 314 330 4.3E-83
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 197 210 4.3E-83
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 775 791 4.3E-83
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 376 396 4.3E-83
Pfam PF00204 DNA gyrase B IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 222 392 3.7E-57
SMART SM00433 topII5 IPR001241 DNA topoisomerase, type IIA 37 799 0.0
CDD cd16928 HATPase_GyrB-like - - 38 217 4.36068E-105
Gene3D G3DSA:3.40.50.670 - IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal 703 804 5.6E-29
PRINTS PR00418 DNA topoisomerase II family signature - - 507 524 2.5E-71
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 33 177 2.1E-29
Pfam PF18053 DNA gyrase B subunit insert domain IPR041423 DNA gyrase subunit B insert domain 566 731 6.6E-55
FunFam G3DSA:3.30.230.10:FF:000005 DNA gyrase subunit B - - 221 394 1.6E-77
Gene3D G3DSA:3.30.230.10 - IPR014721 Small ribosomal subunit protein uS5 domain 2-type fold, subgroup 221 394 9.9E-67
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 221 243 4.3E-83
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 7 17 4.3E-83
PRINTS PR00418 DNA topoisomerase II family signature - - 270 283 2.5E-71
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 4 220 4.0E-95
PRINTS PR00418 DNA topoisomerase II family signature - - 738 754 2.5E-71
Gene3D G3DSA:3.10.20.690 - - - 594 684 1.8E-27
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 182 197 4.3E-83
PRINTS PR00418 DNA topoisomerase II family signature - - 527 539 2.5E-71
Hamap MF_01898 DNA gyrase subunit B [gyrB]. IPR011557 DNA gyrase, subunit B 4 806 101.469612
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 34 176 1.3E-22
Gene3D G3DSA:3.40.50.670 - IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal 395 587 1.8E-80
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 472 481 4.3E-83
PRINTS PR00418 DNA topoisomerase II family signature - - 422 436 2.5E-71
FunFam G3DSA:3.40.50.670:FF:000004 DNA gyrase subunit B - - 706 805 2.8E-50
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 362 376 4.3E-83
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 759 771 4.3E-83
CDD cd03366 TOPRIM_TopoIIA_GyrB IPR034160 DNA gyrase subunit B, TOPRIM domain 420 534 1.05834E-78
FunFam G3DSA:3.40.50.670:FF:000005 DNA gyrase subunit B - - 393 593 1.9E-123
SUPERFAMILY SSF56719 Type II DNA topoisomerase IPR013760 DNA topoisomerase, type IIA-like domain superfamily 396 796 8.37E-88
PRINTS PR01159 DNA gyrase subunit B signature IPR000565 DNA topoisomerase, type IIA, subunit B 244 262 4.3E-83
Pfam PF01751 Toprim domain IPR006171 TOPRIM domain 421 533 4.2E-18
PRINTS PR00418 DNA topoisomerase II family signature - - 489 505 2.5E-71
CDD cd00822 TopoII_Trans_DNA_gyrase - - 221 379 9.06756E-75
Pfam PF00986 DNA gyrase B subunit, carboxyl terminus IPR002288 DNA gyrase B subunit, C-terminal 734 795 8.7E-31
PRINTS PR00418 DNA topoisomerase II family signature - - 72 85 2.5E-71
FunFam G3DSA:3.30.565.10:FF:000002 DNA gyrase subunit B - - 4 220 1.8E-96
PANTHER PTHR45866 DNA GYRASE/TOPOISOMERASE SUBUNIT B - - 3 805 0.0
NCBIfam TIGR01059 JCVI: DNA gyrase subunit B IPR011557 DNA gyrase, subunit B 7 805 0.0
SUPERFAMILY SSF54211 Ribosomal protein S5 domain 2-like IPR020568 Ribosomal protein uS5 domain 2-type superfamily 222 394 4.74E-58

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.