Pseudomonas mendocina NK-01, MDS_3764

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR43707
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006427 histidyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00127
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00127
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004821 histidine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00127
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pmk00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF13393 Histidyl-tRNA synthetase IPR041715 Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain 10 313 5.5E-48
Hamap MF_00127 Histidine--tRNA ligase [hisS]. IPR015807 Histidine-tRNA ligase 3 424 33.000034
NCBIfam TIGR00442 JCVI: histidine--tRNA ligase IPR015807 Histidine-tRNA ligase 6 413 0.0
CDD cd00773 HisRS-like_core IPR041715 Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain 22 310 4.19635E-94
Gene3D G3DSA:3.30.930.10 Bira Bifunctional Protein; Domain 2 IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) 2 326 6.9E-120
Gene3D G3DSA:3.40.50.800 - IPR036621 Anticodon-binding domain superfamily 328 424 3.9E-28
CDD cd00859 HisRS_anticodon IPR033656 Histidyl-anticodon-binding 330 423 2.01252E-26
SUPERFAMILY SSF52954 Class II aaRS ABD-related - - 331 423 5.56E-21
FunFam G3DSA:3.30.930.10:FF:000005 Histidine--tRNA ligase - - 2 323 0.0
SUPERFAMILY SSF55681 Class II aaRS and biotin synthetases IPR045864 Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) 6 320 4.38E-101
Pfam PF03129 Anticodon binding domain IPR004154 Anticodon-binding 332 422 7.5E-8
PANTHER PTHR43707 HISTIDYL-TRNA SYNTHETASE IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit 4 416 7.1E-101
PIRSF PIRSF001549 His-tRNA_synth IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit 1 425 8.1E-116

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.