Pseudomonas syringae pv. tomato DC3000, PSPTO_3514 (topA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0003917 | DNA topoisomerase type I (single strand cut, ATP-independent) activity |
Inferred from Sequence Model
Term mapped from: InterPro:PF08272
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
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| Biological Process | GO:0006265 | DNA topological change |
Inferred from Sequence Model
Term mapped from: InterPro:PF01396
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Cellular Component | GO:0005694 | chromosome |
Inferred from Sequence Model
Term mapped from: InterPro:PF01396
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0003916 | DNA topoisomerase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PF01396
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0003677 | DNA binding |
Inferred from Sequence Model
Term mapped from: InterPro:PF01396
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
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Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Pfam | PF08272 | Topoisomerase I zinc-ribbon-like | IPR013263 | DNA topoisomerase I, zinc ribbon-like, bacterial-type | 827 | 866 | 1.9E-16 |
| PANTHER | PTHR42785 | DNA TOPOISOMERASE, TYPE IA, CORE | IPR000380 | DNA topoisomerase, type IA | 2 | 692 | 0.0 |
| NCBIfam | TIGR01051 | JCVI: type I DNA topoisomerase | IPR005733 | DNA topoisomerase I, bacterial-type | 5 | 639 | 0.0 |
| Gene3D | G3DSA:1.10.290.10 | Topoisomerase I, domain 4 | IPR013826 | DNA topoisomerase, type IA, central region, subdomain 3 | 287 | 411 | 0.0 |
| Pfam | PF01751 | Toprim domain | IPR006171 | TOPRIM domain | 5 | 149 | 2.0E-33 |
| SUPERFAMILY | SSF57783 | Zinc beta-ribbon | - | - | 747 | 809 | 3.06E-17 |
| SMART | SM00436 | topIban2 | IPR003601 | DNA topoisomerase, type IA, domain 2 | 140 | 228 | 2.8E-48 |
| FunFam | G3DSA:3.30.65.10:FF:000002 | DNA topoisomerase 1 | - | - | 589 | 648 | 1.1E-25 |
| SMART | SM00493 | toprim5 | IPR006171 | TOPRIM domain | 3 | 139 | 4.3E-28 |
| SUPERFAMILY | SSF56712 | Prokaryotic type I DNA topoisomerase | IPR023405 | DNA topoisomerase, type IA, core domain | 3 | 614 | 0.0 |
| PRINTS | PR00417 | Prokaryotic DNA topoisomerase I signature | IPR013497 | DNA topoisomerase, type IA, central | 397 | 413 | 1.1E-36 |
| Gene3D | G3DSA:1.10.460.10 | Topoisomerase I, domain 2 | IPR013824 | DNA topoisomerase, type IA, central region, subdomain 1 | 171 | 578 | 0.0 |
| Pfam | PF08272 | Topoisomerase I zinc-ribbon-like | IPR013263 | DNA topoisomerase I, zinc ribbon-like, bacterial-type | 760 | 796 | 4.6E-11 |
| Pfam | PF01131 | DNA topoisomerase | IPR013497 | DNA topoisomerase, type IA, central | 164 | 571 | 4.9E-130 |
| Hamap | MF_00952 | DNA topoisomerase 1 [topA]. | IPR028612 | DNA topoisomerase I, type IA | 3 | 735 | 57.610077 |
| SUPERFAMILY | SSF57783 | Zinc beta-ribbon | - | - | 703 | 746 | 2.38E-8 |
| SUPERFAMILY | SSF57783 | Zinc beta-ribbon | - | - | 812 | 868 | 2.21E-21 |
| PRINTS | PR00417 | Prokaryotic DNA topoisomerase I signature | IPR013497 | DNA topoisomerase, type IA, central | 113 | 126 | 1.1E-36 |
| PRINTS | PR00417 | Prokaryotic DNA topoisomerase I signature | IPR013497 | DNA topoisomerase, type IA, central | 321 | 330 | 1.1E-36 |
| Gene3D | G3DSA:3.30.65.10 | Bacterial Topoisomerase I, domain 1 | - | - | 702 | 747 | 2.2E-11 |
| Gene3D | G3DSA:3.30.65.10 | Bacterial Topoisomerase I, domain 1 | - | - | 590 | 647 | 7.8E-11 |
| PRINTS | PR00417 | Prokaryotic DNA topoisomerase I signature | IPR013497 | DNA topoisomerase, type IA, central | 198 | 216 | 1.1E-36 |
| CDD | cd00186 | TOP1Ac | IPR013497 | DNA topoisomerase, type IA, central | 166 | 582 | 0.0 |
| Pfam | PF01396 | Topoisomerase DNA binding C4 zinc finger | IPR013498 | DNA topoisomerase, type IA, zn finger | 604 | 627 | 0.0035 |
| MobiDBLite | mobidb-lite | consensus disorder prediction | - | - | 37 | 67 | - |
| FunFam | G3DSA:1.10.290.10:FF:000002 | DNA topoisomerase 1 | - | - | 287 | 411 | 7.1E-63 |
| Gene3D | G3DSA:2.20.25.10 | - | - | - | 812 | 868 | 3.3E-26 |
| FunFam | G3DSA:3.40.50.140:FF:000001 | DNA topoisomerase 1 | - | - | 1 | 170 | 1.9E-75 |
| CDD | cd03363 | TOPRIM_TopoIA_TopoI | IPR034149 | DNA topoisomerase 1, TOPRIM domain | 3 | 161 | 1.41345E-59 |
| PRINTS | PR00417 | Prokaryotic DNA topoisomerase I signature | IPR013497 | DNA topoisomerase, type IA, central | 497 | 511 | 1.1E-36 |
| Gene3D | G3DSA:2.70.20.10 | Topoisomerase I, domain 3 | IPR013825 | DNA topoisomerase, type IA, central region, subdomain 2 | 220 | 480 | 0.0 |
| Gene3D | G3DSA:3.40.50.140 | - | - | - | 1 | 170 | 2.8E-65 |
| SMART | SM00437 | topIaneu2 | IPR003602 | DNA topoisomerase, type IA, DNA-binding domain | 279 | 534 | 7.2E-116 |
| Gene3D | G3DSA:3.30.65.10 | Bacterial Topoisomerase I, domain 1 | - | - | 748 | 810 | 2.8E-18 |
| Pfam | PF01396 | Topoisomerase DNA binding C4 zinc finger | IPR013498 | DNA topoisomerase, type IA, zn finger | 713 | 747 | 2.8E-10 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.