Pseudomonas brassicacearum subsp. brassicacearum NFM421, PSEBR_a1750

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006265 DNA topological change
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00952
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00952
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005694 chromosome
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01396
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003917 DNA topoisomerase type I (single strand cut, ATP-independent) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR42785
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003916 DNA topoisomerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00952
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:1.10.290.10:FF:000002 DNA topoisomerase 1 - - 287 411 9.1E-62
Pfam PF01131 DNA topoisomerase IPR013497 DNA topoisomerase, type IA, central 164 571 3.2E-130
MobiDBLite mobidb-lite consensus disorder prediction - - 35 70 -
Pfam PF01751 Toprim domain IPR006171 TOPRIM domain 5 149 4.0E-33
PANTHER PTHR42785 DNA TOPOISOMERASE, TYPE IA, CORE IPR000380 DNA topoisomerase, type IA 2 693 0.0
CDD cd03363 TOPRIM_TopoIA_TopoI IPR034149 DNA topoisomerase 1, TOPRIM domain 3 161 8.18537E-60
PRINTS PR00417 Prokaryotic DNA topoisomerase I signature IPR013497 DNA topoisomerase, type IA, central 497 511 1.0E-36
FunFam G3DSA:3.30.65.10:FF:000002 DNA topoisomerase 1 - - 589 648 1.6E-27
NCBIfam TIGR01051 JCVI: type I DNA topoisomerase IPR005733 DNA topoisomerase I, bacterial-type 5 639 0.0
Pfam PF08272 Topoisomerase I zinc-ribbon-like IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type 828 867 4.3E-20
SUPERFAMILY SSF57783 Zinc beta-ribbon - - 704 747 4.76E-9
Pfam PF01396 Topoisomerase DNA binding C4 zinc finger IPR013498 DNA topoisomerase, type IA, zn finger 714 748 1.4E-11
Pfam PF08272 Topoisomerase I zinc-ribbon-like IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type 761 797 3.7E-11
SUPERFAMILY SSF56712 Prokaryotic type I DNA topoisomerase IPR023405 DNA topoisomerase, type IA, core domain 3 614 0.0
PRINTS PR00417 Prokaryotic DNA topoisomerase I signature IPR013497 DNA topoisomerase, type IA, central 198 216 1.0E-36
Gene3D G3DSA:1.10.460.10 Topoisomerase I, domain 2 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 171 578 0.0
SUPERFAMILY SSF57783 Zinc beta-ribbon - - 748 810 3.74E-17
SUPERFAMILY SSF57783 Zinc beta-ribbon - - 813 869 7.82E-23
Gene3D G3DSA:3.40.50.140 - - - 1 170 8.9E-66
Gene3D G3DSA:3.30.65.10 Bacterial Topoisomerase I, domain 1 - - 590 646 2.9E-11
FunFam G3DSA:3.40.50.140:FF:000001 DNA topoisomerase 1 - - 1 170 1.1E-76
PRINTS PR00417 Prokaryotic DNA topoisomerase I signature IPR013497 DNA topoisomerase, type IA, central 113 126 1.0E-36
PRINTS PR00417 Prokaryotic DNA topoisomerase I signature IPR013497 DNA topoisomerase, type IA, central 321 330 1.0E-36
SMART SM00436 topIban2 IPR003601 DNA topoisomerase, type IA, domain 2 140 228 2.5E-48
SMART SM00437 topIaneu2 IPR003602 DNA topoisomerase, type IA, DNA-binding domain 279 534 5.7E-117
PRINTS PR00417 Prokaryotic DNA topoisomerase I signature IPR013497 DNA topoisomerase, type IA, central 397 413 1.0E-36
Gene3D G3DSA:3.30.65.10 Bacterial Topoisomerase I, domain 1 - - 749 811 8.1E-18
Gene3D G3DSA:3.30.65.10 Bacterial Topoisomerase I, domain 1 - - 704 748 1.4E-12
Gene3D G3DSA:2.20.25.10 - - - 813 869 1.7E-27
Pfam PF01396 Topoisomerase DNA binding C4 zinc finger IPR013498 DNA topoisomerase, type IA, zn finger 604 627 9.6E-4
MobiDBLite mobidb-lite consensus disorder prediction - - 362 389 -
Gene3D G3DSA:1.10.290.10 Topoisomerase I, domain 4 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 287 411 0.0
Hamap MF_00952 DNA topoisomerase 1 [topA]. IPR028612 DNA topoisomerase I, type IA 3 736 57.771378
Gene3D G3DSA:2.70.20.10 Topoisomerase I, domain 3 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 220 480 0.0
CDD cd00186 TOP1Ac IPR013497 DNA topoisomerase, type IA, central 166 582 0.0
SMART SM00493 toprim5 IPR006171 TOPRIM domain 3 139 2.1E-29

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.