Pseudomonas sp. UW4, PputUW4_01339 (mnmC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.150
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008168 methyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR03197
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01266
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004808 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:NF033855
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0008033 tRNA processing
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01102
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF05430
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc tRNA-uridine 2-thiolation (bacteria) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51905 FAD/NAD(P)-binding domain IPR036188 FAD/NAD(P)-binding domain superfamily 263 658 2.59E-34
Pfam PF01266 FAD dependent oxidoreductase IPR006076 FAD dependent oxidoreductase 264 629 4.3E-47
Gene3D G3DSA:3.40.50.150 Vaccinia Virus protein VP39 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily 8 237 1.3E-90
Gene3D G3DSA:3.30.9.10 - - - 345 564 0.0
NCBIfam NF033855 NCBIFAM: tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD IPR047785 tRNA mnm(5)s(2)U biosynthesis bifunctional protein MnmC, N-terminal 18 234 5.2E-73
SUPERFAMILY SSF53335 S-adenosyl-L-methionine-dependent methyltransferases IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily 46 218 7.08E-7
Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC 6 653 25.968803
PANTHER PTHR13847 SARCOSINE DEHYDROGENASE-RELATED - - 258 655 3.5E-43
Gene3D G3DSA:3.50.50.60 - IPR036188 FAD/NAD(P)-binding domain superfamily 262 655 0.0
Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase IPR008471 MnmC-like methyltransferase 114 233 4.8E-40
NCBIfam TIGR03197 JCVI: FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC IPR017610 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, C-terminal 264 658 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.