Pseudomonas protegens Pf-5, PFL_0508 (aceF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016746 transferase activity, transferring acyl groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02817
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0045254 pyruvate dehydrogenase complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006096 glycolytic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004742 dihydrolipoyllysine-residue acetyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pfl01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfl01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfl01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfl00620 Pyruvate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfl00020 Citrate cycle (TCA cycle) 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfl01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfl01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfl00010 Glycolysis / Gluconeogenesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51230 Single hybrid motif IPR011053 Single hybrid motif 226 319 1.27E-21
Pfam PF00364 Biotin-requiring enzyme IPR000089 Biotin/lipoyl attachment 228 299 1.5E-21
Pfam PF00364 Biotin-requiring enzyme IPR000089 Biotin/lipoyl attachment 117 187 1.2E-21
PANTHER PTHR43178 DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX - - 112 216 0.0
FunFam G3DSA:2.40.50.100:FF:000009 Acetyltransferase component of pyruvate dehydrogenase complex - - 225 305 2.2E-27
CDD cd06849 lipoyl_domain - - 5 74 1.36325E-19
NCBIfam TIGR01348 JCVI: dihydrolipoyllysine-residue acetyltransferase IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex 204 649 0.0
CDD cd06849 lipoyl_domain - - 227 299 1.01091E-17
SUPERFAMILY SSF51230 Single hybrid motif IPR011053 Single hybrid motif 115 207 2.09E-22
FunFam G3DSA:3.30.559.10:FF:000004 Acetyltransferase component of pyruvate dehydrogenase complex - - 404 649 1.3E-118
SUPERFAMILY SSF51230 Single hybrid motif IPR011053 Single hybrid motif 4 94 1.01E-22
Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain 420 648 2.0E-77
SUPERFAMILY SSF47005 Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex IPR036625 E3-binding domain superfamily 341 386 1.09E-11
Gene3D G3DSA:2.40.50.100 - - - 115 194 1.4E-21
Pfam PF02817 e3 binding domain IPR004167 Peripheral subunit-binding domain 347 382 3.1E-14
Gene3D G3DSA:3.30.559.10 - IPR023213 Chloramphenicol acetyltransferase-like domain superfamily 407 649 3.7E-87
CDD cd06849 lipoyl_domain - - 116 188 5.22847E-19
SUPERFAMILY SSF52777 CoA-dependent acyltransferases - - 408 649 3.29E-81
FunFam G3DSA:2.40.50.100:FF:000009 Acetyltransferase component of pyruvate dehydrogenase complex - - 114 194 9.3E-29
Gene3D G3DSA:2.40.50.100 - - - 227 304 3.9E-21
FunFam G3DSA:2.40.50.100:FF:000009 Acetyltransferase component of pyruvate dehydrogenase complex - - 1 80 5.1E-30
Gene3D G3DSA:2.40.50.100 - - - 2 80 1.8E-23
Pfam PF00364 Biotin-requiring enzyme IPR000089 Biotin/lipoyl attachment 5 74 5.9E-21
Gene3D G3DSA:4.10.320.10 - IPR036625 E3-binding domain superfamily 335 387 3.9E-17

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.