Pseudomonas protegens Pf-5, PFL_4940 (guaB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003938 IMP dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000130
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00381
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006164 purine nucleotide biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000130
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pfl00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc adenosine nucleotides degradation I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pfl01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc inosine 5'-phosphate degradation InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc guanosine ribonucleotides <i>de novo</i> biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pfl01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM00116 cbs_1 IPR000644 CBS domain 96 143 6.8E-8
SMART SM01240 IMPDH_2 - - 7 475 0.0
Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. IPR005990 Inosine-5'-monophosphate dehydrogenase 8 488 84.14077
Pfam PF00571 CBS domain IPR000644 CBS domain 148 200 0.0041
Pfam PF00478 IMP dehydrogenase / GMP reductase domain IPR001093 IMP dehydrogenase/GMP reductase 8 475 0.0
CDD cd04601 CBS_pair_IMPDH - - 94 202 5.81525E-45
FunFam G3DSA:3.20.20.70:FF:000003 GMP reductase - - 1 488 0.0
NCBIfam TIGR01302 JCVI: IMP dehydrogenase IPR005990 Inosine-5'-monophosphate dehydrogenase 8 456 0.0
CDD cd00381 IMPDH IPR001093 IMP dehydrogenase/GMP reductase 8 464 0.0
PIRSF PIRSF000130 IMPDH IPR005990 Inosine-5'-monophosphate dehydrogenase 1 489 0.0
Pfam PF00571 CBS domain IPR000644 CBS domain 95 139 2.8E-8
SUPERFAMILY SSF51412 Inosine monophosphate dehydrogenase (IMPDH) - - 2 479 8.24E-125
SMART SM00116 cbs_1 IPR000644 CBS domain 157 205 0.006
SUPERFAMILY SSF54631 CBS-domain pair IPR046342 CBS domain superfamily 95 202 2.07E-24
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 2 488 0.0
PANTHER PTHR11911 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED IPR005990 Inosine-5'-monophosphate dehydrogenase 5 483 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.