Pseudomonas protegens CHA0, PFLCHA0_c05160
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0016746 | transferase activity, transferring acyl groups |
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:4.10.320.10
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Cellular Component | GO:0045254 | pyruvate dehydrogenase complex |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0006096 | glycolytic process |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0004742 | dihydrolipoyllysine-residue acetyltransferase activity |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
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|
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | pprc01110 | Biosynthesis of secondary metabolites | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pprc00620 | Pyruvate metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pprc00010 | Glycolysis / Gluconeogenesis | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pprc01130 | Biosynthesis of antibiotics | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pprc01200 | Carbon metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pprc01120 | Microbial metabolism in diverse environments | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pprc01100 | Metabolic pathways | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pprc00020 | Citrate cycle (TCA cycle) | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Pfam | PF00198 | 2-oxoacid dehydrogenases acyltransferase (catalytic domain) | IPR001078 | 2-oxoacid dehydrogenase acyltransferase, catalytic domain | 418 | 646 | 4.1E-77 |
| Gene3D | G3DSA:2.40.50.100 | - | - | - | 113 | 191 | 1.5E-21 |
| CDD | cd06849 | lipoyl_domain | - | - | 5 | 74 | 1.45476E-19 |
| SUPERFAMILY | SSF51230 | Single hybrid motif | IPR011053 | Single hybrid motif | 224 | 317 | 1.27E-21 |
| FunFam | G3DSA:2.40.50.100:FF:000009 | Acetyltransferase component of pyruvate dehydrogenase complex | - | - | 223 | 303 | 2.2E-27 |
| PANTHER | PTHR43178 | DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX | - | - | 111 | 211 | 0.0 |
| Pfam | PF00364 | Biotin-requiring enzyme | IPR000089 | Biotin/lipoyl attachment | 5 | 74 | 5.7E-21 |
| Gene3D | G3DSA:4.10.320.10 | - | IPR036625 | E3-binding domain superfamily | 333 | 385 | 3.8E-17 |
| Pfam | PF00364 | Biotin-requiring enzyme | IPR000089 | Biotin/lipoyl attachment | 226 | 297 | 1.5E-21 |
| SUPERFAMILY | SSF51230 | Single hybrid motif | IPR011053 | Single hybrid motif | 113 | 205 | 3.14E-22 |
| SUPERFAMILY | SSF51230 | Single hybrid motif | IPR011053 | Single hybrid motif | 4 | 94 | 1.44E-22 |
| FunFam | G3DSA:3.30.559.10:FF:000004 | Acetyltransferase component of pyruvate dehydrogenase complex | - | - | 402 | 647 | 8.4E-119 |
| Pfam | PF02817 | e3 binding domain | IPR004167 | Peripheral subunit-binding domain | 345 | 380 | 3.1E-14 |
| Gene3D | G3DSA:3.30.559.10 | - | IPR023213 | Chloramphenicol acetyltransferase-like domain superfamily | 405 | 647 | 5.1E-87 |
| Pfam | PF00364 | Biotin-requiring enzyme | IPR000089 | Biotin/lipoyl attachment | 115 | 185 | 1.1E-21 |
| CDD | cd06849 | lipoyl_domain | - | - | 225 | 297 | 1.03758E-17 |
| Gene3D | G3DSA:2.40.50.100 | - | - | - | 2 | 80 | 1.4E-23 |
| SUPERFAMILY | SSF52777 | CoA-dependent acyltransferases | - | - | 406 | 647 | 4.45E-81 |
| FunFam | G3DSA:2.40.50.100:FF:000009 | Acetyltransferase component of pyruvate dehydrogenase complex | - | - | 1 | 80 | 1.5E-29 |
| NCBIfam | TIGR01348 | JCVI: dihydrolipoyllysine-residue acetyltransferase | IPR006256 | Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex | 201 | 647 | 0.0 |
| CDD | cd06849 | lipoyl_domain | - | - | 114 | 186 | 5.36629E-19 |
| SUPERFAMILY | SSF47005 | Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | IPR036625 | E3-binding domain superfamily | 339 | 384 | 1.09E-11 |
| Gene3D | G3DSA:2.40.50.100 | - | - | - | 225 | 302 | 3.8E-21 |
| FunFam | G3DSA:2.40.50.100:FF:000009 | Acetyltransferase component of pyruvate dehydrogenase complex | - | - | 112 | 192 | 1.3E-28 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.