Pseudomonas denitrificans ATCC 13867, H681_18770 (guaA)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0003922	GMP synthase (glutamine-hydrolyzing) activity	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005524	ATP binding	ISM Inferred from Sequence Model Term mapped from: InterPro:cd01997	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006177	GMP biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006164	purine nucleotide biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:cd01997	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pdr01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pdr00230	Purine metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
NCBIfam	TIGR00884	JCVI: glutamine-hydrolyzing GMP synthase, C-terminal domain	IPR001674	GMP synthase, C-terminal	212	525	0.0
SUPERFAMILY	SSF52317	Class I glutamine amidotransferase-like	IPR029062	Class I glutamine amidotransferase-like	5	204	3.25E-54
Gene3D	G3DSA:3.40.50.620	HUPs	IPR014729	Rossmann-like alpha/beta/alpha sandwich fold	209	410	2.3E-78
Gene3D	G3DSA:3.40.50.880	-	IPR029062	Class I glutamine amidotransferase-like	9	206	2.3E-51
Gene3D	G3DSA:3.30.300.10	-	-	-	411	525	1.0E-48
FunFam	G3DSA:3.30.300.10:FF:000002	GMP synthase [glutamine-hydrolyzing]	-	-	411	525	3.4E-54
PRINTS	PR00096	Glutamine amidotransferase superfamily signature	-	-	81	92	5.1E-7
FunFam	G3DSA:3.40.50.880:FF:000001	GMP synthase [glutamine-hydrolyzing]	-	-	7	206	5.8E-86
PRINTS	PR00099	Carbamoyl-phosphate synthase protein GATase domain signature	-	-	10	24	8.8E-5
PRINTS	PR00097	Anthranilate synthase component II signature	-	-	54	63	1.5E-5
SUPERFAMILY	SSF52402	Adenine nucleotide alpha hydrolases-like	-	-	197	420	4.19E-59
CDD	cd01997	GMP_synthase_C	IPR001674	GMP synthase, C-terminal	229	524	0.0
PRINTS	PR00097	Anthranilate synthase component II signature	-	-	81	92	1.5E-5
PRINTS	PR00096	Glutamine amidotransferase superfamily signature	-	-	54	63	5.1E-7
Pfam	PF00958	GMP synthase C terminal domain	IPR001674	GMP synthase, C-terminal	433	524	9.2E-41
Pfam	PF00117	Glutamine amidotransferase class-I	IPR017926	Glutamine amidotransferase	12	200	5.6E-36
Hamap	MF_00344	GMP synthase [glutamine-hydrolyzing] [guaA].	IPR022955	GMP synthase	7	525	56.074688
SUPERFAMILY	SSF54810	GMP synthetase C-terminal dimerisation domain	-	-	405	525	9.29E-50
CDD	cd01742	GATase1_GMP_Synthase	IPR004739	GMP synthase, glutamine amidotransferase	10	198	2.87791E-95
PRINTS	PR00099	Carbamoyl-phosphate synthase protein GATase domain signature	-	-	81	97	8.8E-5
PRINTS	PR00099	Carbamoyl-phosphate synthase protein GATase domain signature	-	-	51	65	8.8E-5
PRINTS	PR00097	Anthranilate synthase component II signature	-	-	177	190	1.5E-5
Pfam	PF02540	NAD synthase	IPR022310	NAD/GMP synthase	218	291	3.1E-8
FunFam	G3DSA:3.40.50.620:FF:000001	GMP synthase [glutamine-hydrolyzing]	-	-	209	410	1.5E-101
PRINTS	PR00096	Glutamine amidotransferase superfamily signature	-	-	177	190	5.1E-7
NCBIfam	TIGR00888	JCVI: glutamine-hydrolyzing GMP synthase, N-terminal domain	IPR004739	GMP synthase, glutamine amidotransferase	10	205	8.8E-77
PANTHER	PTHR11922	GMP SYNTHASE-RELATED	-	-	10	525	0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.