Pseudomonas aeruginosa LESB58, PALES_12581 (lasB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0060309 elastin catabolic process
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA3724
 ECO:0000249
sequence similarity evidence used in automatic assertion		 1902216
Biological Process GO:0051542 elastin biosynthetic process
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA3724
 ECO:0000249
sequence similarity evidence used in automatic assertion		 1902216
Molecular Function GO:0004222 metalloendopeptidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00730
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006508 proteolysis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00730
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Secreted Factors (toxins, enzymes, alginate) Other LESB58 genes in this class
Translation, post-translational modification, degradation Other LESB58 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.10.450.40 - - - 118 197 4.2E-22
PRINTS PR00730 Thermolysin metalloprotease (M4) family signature IPR023612 Peptidase M4 336 352 5.8E-26
Gene3D G3DSA:1.10.390.10 Neutral Protease Domain 2 IPR027268 Peptidase M4/M1, CTD superfamily 350 497 3.5E-49
Pfam PF03413 Peptidase propeptide and YPEB domain IPR025711 PepSY domain 123 192 8.8E-9
PRINTS PR00730 Thermolysin metalloprotease (M4) family signature IPR023612 Peptidase M4 357 368 5.8E-26
Pfam PF01447 Thermolysin metallopeptidase, catalytic domain IPR013856 Peptidase M4 domain 208 345 3.4E-33
FunFam G3DSA:3.10.170.10:FF:000002 Elastase - - 198 349 9.9E-98
Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif IPR011096 FTP domain 56 90 3.0E-6
PANTHER PTHR33794 BACILLOLYSIN - - 34 492 7.3E-104
PRINTS PR00730 Thermolysin metalloprotease (M4) family signature IPR023612 Peptidase M4 419 435 5.8E-26
PRINTS PR00730 Thermolysin metalloprotease (M4) family signature IPR023612 Peptidase M4 302 322 5.8E-26
CDD cd09597 M4_TLP - - 234 492 8.53745E-101
SUPERFAMILY SSF55486 Metalloproteases ("zincins"), catalytic domain - - 199 494 1.41E-88
Gene3D G3DSA:3.10.170.10 - - - 198 349 1.8E-56
Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain IPR001570 Peptidase M4, C-terminal 348 492 1.0E-36
Gene3D G3DSA:3.10.450.490 - - - 30 115 1.1E-11

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.