Pseudomonas aeruginosa LESB58, PALES_53321 (mutL)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Cellular Component	GO:0032300	mismatch repair complex	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR10073	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006298	mismatch repair	ISM Inferred from Sequence Model Term mapped from: InterPro:SM01340	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016887	ATPase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR10073	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0030983	mismatched DNA binding	ISM Inferred from Sequence Model Term mapped from: InterPro:SM01340	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0140664	ATP-dependent DNA damage sensor activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR10073	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005524	ATP binding	ISM Inferred from Sequence Model Term mapped from: InterPro:SM01340	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other LESB58 genes in this class

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Pfam	PF13589	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	29	125	4.0E-9
PANTHER	PTHR10073	DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL	IPR038973	DNA mismatch repair protein MutL/Mlh/Pms-like	447	620	1.4E-125
SMART	SM01340	DNA_mis_repair_2	IPR013507	DNA mismatch repair protein, S5 domain 2-like	216	334	8.4E-63
NCBIfam	TIGR00585	JCVI: DNA mismatch repair endonuclease MutL	IPR002099	DNA mismatch repair protein MutL/Mlh/PMS	7	558	0.0
Gene3D	G3DSA:3.30.565.10	-	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	6	220	1.1E-70
MobiDBLite	mobidb-lite	consensus disorder prediction	-	-	337	364	-
SUPERFAMILY	SSF54211	Ribosomal protein S5 domain 2-like	IPR020568	Ribosomal protein uS5 domain 2-type superfamily	195	334	8.34E-41
CDD	cd16926	HATPase_MutL-MLH-PMS-like	-	-	14	201	9.97311E-109
FunFam	G3DSA:3.30.230.10:FF:000013	DNA mismatch repair endonuclease MutL	-	-	221	332	1.5E-54
SMART	SM00853	MutL_C_2	IPR014790	MutL, C-terminal, dimerisation	446	589	4.9E-57
Gene3D	G3DSA:3.30.1370.100	-	IPR042121	MutL, C-terminal domain, regulatory subdomain	489	584	1.6E-58
Hamap	MF_00149	DNA mismatch repair protein MutL [mutL].	IPR020667	DNA mismatch repair protein, MutL	5	629	29.842117
CDD	cd03482	MutL_Trans_MutL	-	-	212	333	1.43583E-72
Gene3D	G3DSA:3.30.1540.20	-	IPR042120	MutL, C-terminal domain, dimerisation subdomain	449	626	1.6E-58
FunFam	G3DSA:3.30.565.10:FF:000003	DNA mismatch repair endonuclease MutL	-	-	5	216	8.6E-83
MobiDBLite	mobidb-lite	consensus disorder prediction	-	-	383	405	-
SUPERFAMILY	SSF55874	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	5	206	1.83E-54
Pfam	PF01119	DNA mismatch repair protein, C-terminal domain	IPR013507	DNA mismatch repair protein, S5 domain 2-like	218	333	1.4E-40
SUPERFAMILY	SSF118116	DNA mismatch repair protein MutL	IPR037198	MutL, C-terminal domain superfamily	442	631	2.62E-62
Pfam	PF08676	MutL C terminal dimerisation domain	IPR014790	MutL, C-terminal, dimerisation	442	589	1.8E-51
FunFam	G3DSA:3.30.1370.100:FF:000005	DNA mismatch repair protein MutL	-	-	489	584	6.9E-50
Gene3D	G3DSA:3.30.230.10	-	IPR014721	Small ribosomal subunit protein uS5 domain 2-type fold, subgroup	221	331	3.1E-32

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.