Pseudomonas aeruginosa 2192, PA2G_03824

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016791 phosphatase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA5484
 ECO:0000249
sequence similarity evidence used in automatic assertion		 23024348
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00388
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00388
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00672
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other 2192 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 526 540 5.1E-19
Gene3D G3DSA:1.10.287.130 - - - 365 445 2.6E-15
Gene3D G3DSA:1.10.8.500 HAMP domain in histidine kinase - - 194 245 7.4E-9
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 489 595 7.3E-33
SMART SM00091 pas_2 IPR000014 PAS domain 258 323 1.2E-5
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 491 594 3.0E-24
Gene3D G3DSA:3.30.450.20 PAS domain - - 247 364 1.4E-16
SMART SM00388 HisKA_10 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 375 443 1.1E-16
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 376 443 6.8E-12
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 557 575 5.1E-19
FunFam G3DSA:3.30.565.10:FF:000006 Sensor histidine kinase WalK - - 448 595 6.8E-39
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 246 367 1.68E-13
PANTHER PTHR44936 SENSOR PROTEIN CREC - - 5 594 0.0
CDD cd06225 HAMP - - 200 242 3.29986E-9
NCBIfam TIGR00229 JCVI: PAS domain S-box protein IPR000014 PAS domain 257 373 3.4E-7
SMART SM00304 HAMP_11 IPR003660 HAMP domain 195 247 4.1E-12
Pfam PF00672 HAMP domain IPR003660 HAMP domain 193 244 1.6E-11
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 544 554 5.1E-19
SUPERFAMILY SSF158472 HAMP domain-like - - 195 245 3.79E-8
Pfam PF08448 PAS fold IPR013656 PAS fold-4 264 370 9.5E-11
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 432 595 3.67E-46
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 447 595 7.9E-46
Pfam PF16767 Sensor domain of alginate biosynthesis sensor protein KinB IPR031909 Alginate biosynthesis sensor protein KinB, sensor domain 42 160 6.9E-40
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 373 439 2.76964E-12
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 360 443 1.22E-15
Gene3D G3DSA:1.20.120.880 Histidine kinase (KinB), sensor domain IPR038320 KinB, N-terminal domain superfamily 39 168 1.4E-35
CDD cd00075 HATPase - - 494 593 6.08836E-37
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 581 594 5.1E-19
CDD cd00130 PAS IPR000014 PAS domain 267 366 9.24072E-6
CDD cd19409 KinB_sensor IPR031909 Alginate biosynthesis sensor protein KinB, sensor domain 47 157 1.46783E-39

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.