Pseudomonas aeruginosa PACS2, A0K_RS21475

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF05430
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008168 methyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR03197
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53335
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0008033 tRNA processing
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01102
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004808 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:NF033855
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01266
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Hypothetical, unclassified, unknown Other PACS2 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc tRNA-uridine 2-thiolation (bacteria) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF53335 S-adenosyl-L-methionine-dependent methyltransferases IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily 9 205 1.81E-6
Pfam PF01266 FAD dependent oxidoreductase IPR006076 FAD dependent oxidoreductase 259 622 1.3E-49
Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC 5 646 27.123299
PANTHER PTHR13847 SARCOSINE DEHYDROGENASE-RELATED - - 253 650 3.9E-49
Gene3D G3DSA:3.40.50.150 Vaccinia Virus protein VP39 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily 7 239 1.4E-93
NCBIfam NF033855 NCBIFAM: tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD IPR047785 tRNA mnm(5)s(2)U biosynthesis bifunctional protein MnmC, N-terminal 17 233 4.9E-72
NCBIfam TIGR03197 JCVI: FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC IPR017610 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, C-terminal 258 651 0.0
Gene3D G3DSA:3.50.50.60 - IPR036188 FAD/NAD(P)-binding domain superfamily 257 648 0.0
Gene3D G3DSA:3.30.9.10 - - - 339 557 0.0
Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase IPR008471 MnmC-like methyltransferase 112 234 7.2E-45
SUPERFAMILY SSF51905 FAD/NAD(P)-binding domain IPR036188 FAD/NAD(P)-binding domain superfamily 259 650 2.07E-36
SUPERFAMILY SSF54373 FAD-linked reductases, C-terminal domain - - 465 543 5.89E-6

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.