Pseudomonas fluorescens Pf0-1, Pfl01_1044

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas fluorescens Pf0-1
GCF_000012445.1|latest
Locus Tag
Pfl01_1044
Name
Replicon chromosome
Genomic location 1209730 - 1211154 (- strand)

Cross-References

RefSeq YP_346776.1
GI 77457271
EC Number 1.2.1.8
Entrez 3716174
INSDC ABA72787.1
NCBI Locus Tag Pfl01_1044
UniParc UPI0000388490
UniProtKB Acc Q3KHG9
UniProtKB ID Q3KHG9_PSEPF
UniRef100 UniRef100_Q3KHG9
UniRef50 UniRef50_Q8ZPC9
UniRef90 UniRef90_G8QB50

Product

Feature Type CDS
Coding Frame 1
Product Name
gamma-aminobutyraldehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -11.49
Kyte-Doolittle Hydrophobicity Value -0.040
Molecular Weight (kDa) 50940.4
Isoelectric Point (pI) 5.18

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
[Formylmethyl]Trimethyl-Ammonium, N,N,N-Trimethylammonium Acetaldehyde DB04401 DrugBank 5.1.4 P77674 Gamma-aminobutyraldehyde dehydrogenase 75.3 474 8.2e-209

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG013848 (352 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Pfl01_1044

Human Homologs

Ensembl 110, assembly GRCh38.p14
aldehyde dehydrogenase 1 family member A2 [Source:HGNC Symbol;Acc:HGNC:15472]
E-value: 1.7e-94
Percent Identity: 39.8
Ensembl 110, assembly GRCh38.p14
aldehyde dehydrogenase 1 family member A2 [Source:HGNC Symbol;Acc:HGNC:15472]
E-value: 1.7e-94
Percent Identity: 39.8

References

No references are associated with this feature.