Pseudomonas fluorescens Pf0-1, Pfl01_3107 (metH)

Gene Feature Overview

Strain	Pseudomonas fluorescens Pf0-1 GCF_000012445.1|latest
Locus Tag	Pfl01_3107
Name	metH
Replicon	chromosome
Genomic location	3560284 - 3563994 (+ strand)

Cross-References

RefSeq	YP_348836.1
GI	77459329
EC Number	2.1.1.13
Entrez	3712794
INSDC	ABA74845.1
NCBI Locus Tag	Pfl01_3107
UniParc	UPI000022F3DF
UniProtKB Acc	Q3KBK9
UniProtKB ID	Q3KBK9_PSEPF
UniRef100	UniRef100_Q3KBK9
UniRef50	UniRef50_P13009
UniRef90	UniRef90_G8Q6L5

Product

Feature Type	CDS
Coding Frame	1
Product Name	B12-dependent methionine synthase
Synonyms
Evidence for Translation
Charge (pH 7)	-47.75
Kyte-Doolittle Hydrophobicity Value	-0.178
Molecular Weight (kDa)	135774.0
Isoelectric Point (pI)	4.71

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Analysis not done

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG003557 (535 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: Pfl01_3107 Search term: metH Search term: B12-dependent methionine synthase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000502299 5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468] E-value: 0.0e+00 Percent Identity: 54.2
Ensembl 110, assembly GRCh38.p14	ENSP00000506109 5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468] E-value: 0.0e+00 Percent Identity: 51.2
Ensembl 110, assembly GRCh38.p14	ENSP00000441845 5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468] E-value: 0.0e+00 Percent Identity: 51.9
Ensembl 110, assembly GRCh38.p14	ENSP00000505600 5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468] E-value: 0.0e+00 Percent Identity: 52.2
Ensembl 110, assembly GRCh38.p14	ENSP00000355536 5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468] E-value: 0.0e+00 Percent Identity: 54.6
Ensembl 110, assembly GRCh38.p14	ENSP00000506327 5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468] E-value: 0.0e+00 Percent Identity: 48.4

References