Pseudomonas putida S16, PPS_0160

Gene Feature Overview

Strain	Pseudomonas putida S16 GCF_000219705.1|latest
Locus Tag	PPS_0160
Name
Replicon	chromosome
Genomic location	191104 - 192045 (+ strand)

Cross-References

RefSeq	YP_004699629.1
GI	339485101
Entrez	10935832
INSDC	AEJ10749.1
NCBI Locus Tag	PPS_0160
UniParc	UPI0002172482
UniProtKB Acc	F8FVP8
UniProtKB ID	F8FVP8_PSEP6
UniRef100	UniRef100_F8FVP8
UniRef50	UniRef50_Q4K3X3
UniRef90	UniRef90_Q88RE5

Product

Feature Type	CDS
Coding Frame	1
Product Name	porphobilinogen deaminase
Synonyms
Evidence for Translation
Charge (pH 7)	-4.70
Kyte-Doolittle Hydrophobicity Value	0.017
Molecular Weight (kDa)	33447.9
Isoelectric Point (pI)	5.69

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 586 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG004841 (536 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PPS_0160 Search term: porphobilinogen deaminase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000376584 hydroxymethylbilane synthase [Source:HGNC Symbol;Acc:HGNC:4982] E-value: 2.2e-61 Percent Identity: 42.6
Ensembl 110, assembly GRCh38.p14	ENSP00000497255 hydroxymethylbilane synthase [Source:HGNC Symbol;Acc:HGNC:4982] E-value: 2.2e-61 Percent Identity: 42.6
Ensembl 110, assembly GRCh38.p14	ENSP00000498786 hydroxymethylbilane synthase [Source:HGNC Symbol;Acc:HGNC:4982] E-value: 2.2e-61 Percent Identity: 42.6
Ensembl 110, assembly GRCh38.p14	ENSP00000444730 hydroxymethylbilane synthase [Source:HGNC Symbol;Acc:HGNC:4982] E-value: 2.2e-61 Percent Identity: 42.6

References