Pseudomonas putida HB3267, B479_12155 (ureC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas putida HB3267
GCF_000325725.1|latest
Locus Tag
B479_12155
Name
ureC
Replicon chromosome
Genomic location 2670618 - 2672321 (+ strand)

Cross-References

RefSeq YP_007229270.1
GI 431802367
EC Number 3.5.1.5
Entrez 14288818
INSDC AGA73327.1
NCBI Locus Tag B479_12155
UniParc UPI000217371F
UniProtKB Acc L0FJ45
UniProtKB ID L0FJ45_PSEPU
UniRef100 UniRef100_A0A099N0T1
UniRef50 UniRef50_P17086
UniRef90 UniRef90_Q88J04

Product

Feature Type CDS
Coding Frame 1
Product Name
urease subunit alpha
Synonyms
Evidence for Translation
Charge (pH 7) -13.17
Kyte-Doolittle Hydrophobicity Value 0.005
Molecular Weight (kDa) 60.6
Isoelectric Point (pI) 5.85

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
Urea C-14 DB09513 DrugBank 5.1.4 Q8KT33 Urease 67.1 377 7.9e-146
Urea C-13 DB09510 DrugBank 5.1.4 Q8KT33 Urease 67.1 377 7.9e-146

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 242 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004496 (523 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: B479_12155
Search term: ureC

Human Homologs

References

No references are associated with this feature.