Pseudomonas putida HB3267, B479_19045

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas putida HB3267
GCF_000325725.1|latest
Locus Tag
B479_19045
Name
Replicon chromosome
Genomic location 4198480 - 4200441 (- strand)

Cross-References

RefSeq YP_007230644.1
GI 431803741
EC Number 6.2.1.1
Entrez 14290192
INSDC AGA74701.1
NCBI Locus Tag B479_19045
UniParc UPI0002A15787
UniProtKB Acc L0FPN6
UniProtKB ID L0FPN6_PSEPU
UniRef100 UniRef100_V9X1D9
UniRef50 UniRef50_Q885K7
UniRef90 UniRef90_Q885K7

Product

Feature Type CDS
Coding Frame 1
Product Name
acetyl-CoA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -7.41
Kyte-Doolittle Hydrophobicity Value -0.182
Molecular Weight (kDa) 71.8
Isoelectric Point (pI) 6.35

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Drugs Targeting this Protein

Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.

Drug Name Source Accession Source DB Version Target Accession Target Description Percent Identity Alignment Length E-Value
Adenosine-5'-Propylphosphate DB03230 DrugBank 5.1.4 Q8ZKF6 Acetyl-coenzyme A synthetase 68.3 652 1.4e-275
Coenzyme A DB01992 DrugBank 5.1.4 Q8ZKF6 Acetyl-coenzyme A synthetase 68.3 652 1.4e-275

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 584 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000854 (1000 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: B479_19045

Human Homologs

Ensembl 110, assembly GRCh38.p14
acyl-CoA synthetase short chain family member 2 [Source:HGNC Symbol;Acc:HGNC:15814]
E-value: 1.5e-202
Percent Identity: 53.4

References

No references are associated with this feature.