Pseudomonas putida HB3267, B479_24625

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas putida HB3267
GCF_000325725.1|latest
Locus Tag
B479_24625
Name
Replicon chromosome
Genomic location 5434321 - 5435853 (- strand)

Cross-References

RefSeq YP_007231757.1
GI 431804854
EC Number 4.3.1.3
Entrez 14291305
INSDC AGA75814.1
NCBI Locus Tag B479_24625
UniParc UPI0002A17156
UniProtKB Acc L0FPC9
UniProtKB ID L0FPC9_PSEPU
UniRef100 UniRef100_L0FPC9
UniRef50 UniRef50_P21310
UniRef90 UniRef90_P21310

Product

Feature Type CDS
Coding Frame 1
Product Name
histidine ammonia-lyase
Synonyms
Evidence for Translation
Charge (pH 7) -7.07
Kyte-Doolittle Hydrophobicity Value 0.112
Molecular Weight (kDa) 53818.0
Isoelectric Point (pI) 6.06

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
1GK2 LYASE 08/07/01 Histidine Ammonia-Lyase (HAL) Mutant F329G from Pseudomonas putida PSEUDOMONAS PUTIDA 1.9 X-RAY DIFFRACTION 97.4
1EB4 LYASE 07/19/01 Histidine Ammonia-Lyase (HAL) Mutant F329A from Pseudomonas putida PSEUDOMONAS PUTIDA 2 X-RAY DIFFRACTION 97.4
1B8F LYASE 01/31/99 Histidine ammonia-lyase (HAL) from Pseudomonas putida Pseudomonas putida 2.1 X-RAY DIFFRACTION 97.6
1GKM LYASE 08/16/01 HISTIDINE AMMONIA-LYASE (HAL) FROM PSEUDOMONAS PUTIDA INHIBITED WITH L-CYSTEINE PSEUDOMONAS PUTIDA 1 X-RAY DIFFRACTION 97.6
1GKJ LYASE 08/15/01 Histidine Ammonia-Lyase (HAL) Mutant Y280F from Pseudomonas putida PSEUDOMONAS PUTIDA 1.7 X-RAY DIFFRACTION 97.4
1GK3 LYASE 08/07/01 Histidine Ammonia-Lyase (HAL) Mutant D145A from Pseudomonas putida PSEUDOMONAS PUTIDA 2.25 X-RAY DIFFRACTION 97.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 301 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004694 (505 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: B479_24625

Human Homologs

Ensembl 110, assembly GRCh38.p14
histidine ammonia-lyase [Source:HGNC Symbol;Acc:HGNC:4806]
E-value: 1.2e-106
Percent Identity: 44.3

References

No references are associated with this feature.