Pseudomonas aeruginosa PA7, PSPA7_1050 (thiL)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PA7 GCF_000017205.1|latest
Locus Tag	PSPA7_1050
Name	thiL
Replicon	chromosome
Genomic location	1049818 - 1050786 (+ strand)

Cross-References

RefSeq	YP_001346436.1
GI	152986111
EC Number	2.7.4.16
Entrez	5354812
INSDC	ABR83294.1
NCBI Locus Tag	PSPA7_1050
UniParc	UPI0000D728C3
UniProtKB Acc	A6V051
UniProtKB ID	A6V051_PSEA7
UniRef100	UniRef100_A6V051
UniRef50	UniRef50_Q9HWX7
UniRef90	UniRef90_Q9HWX7

Product

Feature Type	CDS
Coding Frame	1
Product Name	thiamine monophosphate kinase
Synonyms
Evidence for Translation
Charge (pH 7)	-13.00
Kyte-Doolittle Hydrophobicity Value	0.366
Molecular Weight (kDa)	32945.3
Isoelectric Point (pI)	4.47

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
7DU3	PROTEIN BINDING	01/07/21	ThiL in complex with AMP-PNP	Pseudomonas aeruginosa	2.54	X-RAY DIFFRACTION	96.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 540 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001633 (533 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSPA7_1050 Search term: thiL Search term: thiamine monophosphate kinase

Human Homologs

References