Pseudomonas aeruginosa PA7, PSPA7_2154

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_2154
Name
Replicon chromosome
Genomic location 2208435 - 2209505 (+ strand)

Cross-References

RefSeq YP_001347526.1
GI 152985094
Entrez 5353658
NCBI Locus Tag PSPA7_2154

Product

Feature Type CDS
Coding Frame 1
Product Name
beta-hexosaminidase
Synonyms
Evidence for Translation
Charge (pH 7) -0.50
Kyte-Doolittle Hydrophobicity Value -0.023
Molecular Weight (kDa) 38756.2
Isoelectric Point (pI) 6.91

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5G6T HYDROLASE 07/15/16 Crystal structure of Zn-containing NagZ H174A mutant from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 2.15 X-RAY DIFFRACTION 94.9
5G5K HYDROLASE 05/25/16 Crystal structure of NagZ from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin PSEUDOMONAS AERUGINOSA 3.1 X-RAY DIFFRACTION 95.2
5G1M HYDROLASE 03/28/16 Crystal structure of NagZ from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 1.8 X-RAY DIFFRACTION 95.2
5LY7 GENE REGULATION 09/25/16 Crystal structure of NagZ H174A mutant from Pseudomonas aeruginosa in complex with the inhibitor 2-acetamido-1,2-dideoxynojirimycin Pseudomonas aeruginosa 3.1 X-RAY DIFFRACTION 94.9
5G3R HYDROLASE 04/30/16 Crystal structure of NagZ from Pseudomonas aeruginosa in complex with N-acetylglucosamine and L-Ala-1,6-anhydroMurNAc PSEUDOMONAS AERUGINOSA 2.18 X-RAY DIFFRACTION 95.2
5G2M HYDROLASE 04/09/16 Crystal structure of NagZ from Pseudomonas aeruginosa in complex with N-acetylglucosamine PSEUDOMONAS AERUGINOSA 3 X-RAY DIFFRACTION 95.2
5G5U HYDROLASE 06/05/16 Crystal structure of NagZ H174A mutant from Pseudomonas aeruginosa PSEUDOMONAS AERUGINOSA 2.25 X-RAY DIFFRACTION 94.9

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 484 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002577 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_2154

Human Homologs

References

No references are associated with this feature.