Pseudomonas aeruginosa PA7, PSPA7_2746 (mexT)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_2746
Name
mexT
Replicon chromosome
Genomic location 2771096 - 2772010 (- strand)

Cross-References

RefSeq YP_001348106.1
GI 152984096
Entrez 5356246
INSDC ABR81279.1
NCBI Locus Tag PSPA7_2746
UniParc UPI0000D73025
UniProtKB Acc A6V4X1
UniProtKB ID A6V4X1_PSEA7
UniRef100 UniRef100_A6V4X1
UniRef50 UniRef50_Q9I0Z0
UniRef90 UniRef90_A6V4X1

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator MexT
Synonyms
Evidence for Translation
Charge (pH 7) 0.70
Kyte-Doolittle Hydrophobicity Value -0.074
Molecular Weight (kDa) 33.4
Isoelectric Point (pI) 7.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
MexT MexT is a LysR-type transcriptional activator that positively regulates the expression of MexEF-OprN, OprD, and MexS. [PMID:11040437, PMID:26833155, PMID:10515918] ARO:3000814 protein overexpression model Strict 523.5 99.26 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6L33 TRANSCRIPTION 10/08/19 Crystal structure of the regulatory domain of MexT, a transcriptional activator in Pseudomonas aeruginosa Pseudomonas aeruginosa 2 X-RAY DIFFRACTION 99.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 324 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001179 (1943 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_2746
Search term: mexT

Human Homologs

References

No references are associated with this feature.