Pseudomonas aeruginosa PA7, PSPA7_3277

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_3277
Name
Replicon chromosome
Genomic location 3390850 - 3392817 (+ strand)

Cross-References

RefSeq YP_001348637.1
GI 152988409
Entrez 5356544
INSDC ABR85592.1
NCBI Locus Tag PSPA7_3277
UniParc UPI0000D72AD3
UniProtKB Acc A6V6F2
UniProtKB ID A6V6F2_PSEA7
UniRef100 UniRef100_A6V6F2
UniRef50 UniRef50_Q9I299
UniRef90 UniRef90_Q9I299

Product

Feature Type CDS
Coding Frame 1
Product Name
alpha subunit of geranoyl-CoA carboxylase, GnyA
Synonyms
Evidence for Translation
Charge (pH 7) -16.34
Kyte-Doolittle Hydrophobicity Value -0.182
Molecular Weight (kDa) 70876.6
Isoelectric Point (pI) 5.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3U9S LIGASE 10/19/11 Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC) 750 kD holoenzyme, CoA complex Pseudomonas aeruginosa 3.5 X-RAY DIFFRACTION 96.5
3U9T LIGASE 10/19/11 Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC) 750 kD holoenzyme, free enzyme Pseudomonas aeruginosa 2.9 X-RAY DIFFRACTION 96.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 643 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003427 (523 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_3277

Human Homologs

Ensembl 110, assembly GRCh38.p14
methylcrotonyl-CoA carboxylase subunit 1 [Source:HGNC Symbol;Acc:HGNC:6936]
E-value: 3.9e-161
Percent Identity: 45.8

References

No references are associated with this feature.