Pseudomonas aeruginosa PA7, PSPA7_3768 (acnA)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PA7 GCF_000017205.1|latest
Locus Tag	PSPA7_3768
Name	acnA
Replicon	chromosome
Genomic location	3900817 - 3903549 (+ strand)

Cross-References

RefSeq	YP_001349122.1
GI	152984215
EC Number	4.2.1.3
Entrez	5355562
NCBI Locus Tag	PSPA7_3768

Product

Feature Type	CDS
Coding Frame	1
Product Name	aconitate hydratase
Synonyms
Evidence for Translation
Charge (pH 7)	-19.55
Kyte-Doolittle Hydrophobicity Value	-0.222
Molecular Weight (kDa)	99203.0
Isoelectric Point (pI)	5.28

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 616 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000767 (1061 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSPA7_3768 Search term: acnA Search term: aconitate hydratase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000309477 aconitase 1 [Source:HGNC Symbol;Acc:HGNC:117] E-value: 4.4e-264 Percent Identity: 52.9
Ensembl 110, assembly GRCh38.p14	ENSP00000369255 aconitase 1 [Source:HGNC Symbol;Acc:HGNC:117] E-value: 4.4e-264 Percent Identity: 52.9
Ensembl 110, assembly GRCh38.p14	ENSP00000438733 aconitase 1 [Source:HGNC Symbol;Acc:HGNC:117] E-value: 4.4e-264 Percent Identity: 52.9

References