Pseudomonas aeruginosa PA7, PSPA7_4583 (ldhA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_4583
Name
ldhA
Replicon chromosome
Genomic location 4706776 - 4707765 (+ strand)

Cross-References

RefSeq YP_001349931.1
GI 152985530
Entrez 5357605
INSDC ABR82713.1
NCBI Locus Tag PSPA7_4583
UniParc UPI0000D724F0
UniProtKB Acc A6VA46
UniProtKB ID A6VA46_PSEA7
UniRef100 UniRef100_A6VA46
UniRef50 UniRef50_Q1IDM4
UniRef90 UniRef90_Q9I530

Product

Feature Type CDS
Coding Frame 1
Product Name
D-lactate dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -6.72
Kyte-Doolittle Hydrophobicity Value 0.004
Molecular Weight (kDa) 35.8
Isoelectric Point (pI) 6.14

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5Z20 OXIDOREDUCTASE 12/28/17 The ternary structure of D-lactate dehydrogenase from Pseudomonas aeruginosa with NADH and oxamate Pseudomonas aeruginosa 2.2 X-RAY DIFFRACTION 96.4
6ABJ OXIDOREDUCTASE 07/21/18 The apo-structure of D-lactate dehydrogenase from Pseudomonas aeruginosa Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.86 X-RAY DIFFRACTION 96.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 640 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000893 (1006 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_4583
Search term: ldhA

Human Homologs

References

No references are associated with this feature.