Pseudomonas aeruginosa PA7, PSPA7_4610 (csrA)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PA7 GCF_000017205.1|latest
Locus Tag	PSPA7_4610
Name	csrA
Replicon	chromosome
Genomic location	4728559 - 4728744 (- strand)

Cross-References

RefSeq	YP_001349954.1
GI	152984373
Entrez	5358298
INSDC	ABR81556.1
NCBI Locus Tag	PSPA7_4610
UniParc	UPI00001285B6
UniProtKB Acc	A6VA69
UniProtKB ID	A6VA69_PSEA7
UniRef100	UniRef100_B7UY29
UniRef50	UniRef50_Q5E7G3
UniRef90	UniRef90_A4VJB5

Product

Feature Type	CDS
Coding Frame	1
Product Name	carbon storage regulator
Synonyms
Evidence for Translation
Charge (pH 7)	0.46
Kyte-Doolittle Hydrophobicity Value	-0.446
Molecular Weight (kDa)	6.9
Isoelectric Point (pI)	7.70

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown Class 3 20472543
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name	Definition	Accession	Model Type (?)	SNP	Cutoff	Bit Score	Percent Identity	CARD Version
rsmA	rsmA is a gene that regulates virulence of Pseudomonas aeruginosa. However, its negative effect on MexEF-OprN overexpression has been noted to confer resistance to various antibiotics. It's Escherichia coli homolog is csrA. [PMID:16622241, PMID:11673439]	ARO:3005069	protein homolog model		Perfect	117.1	100.0	3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
7YR7	RNA BINDING PROTEIN/RNA	08/09/22	Cryo-EM structure of Pseudomonas aeruginosa RsmZ RNA in complex with three RsmA protein dimers	Pseudomonas aeruginosa	3.8	ELECTRON MICROSCOPY	100.0
7YR6	RNA BINDING PROTEIN/RNA	08/09/22	Cryo-EM structure of Pseudomonas aeruginosa RsmZ RNA in complex with two RsmA protein dimers	Pseudomonas aeruginosa	4.8	ELECTRON MICROSCOPY	100.0
1VPZ	RNA BINDING PROTEIN	11/24/04	Crystal structure of a putative carbon storage regulator protein (csra, pa0905) from pseudomonas aeruginosa at 2.05 A resolution	Pseudomonas aeruginosa	2.05	X-RAY DIFFRACTION	100.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 227 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000872 (536 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSPA7_4610 Search term: csrA Search term: carbon storage regulator

Human Homologs

References