Pseudomonas aeruginosa PA7, PSPA7_4727 (prpD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_4727
Name
prpD
Replicon chromosome
Genomic location 4853304 - 4854788 (+ strand)

Cross-References

RefSeq YP_001350068.1
GI 152984596
EC Number 4.2.1.79
Entrez 5358552
NCBI Locus Tag PSPA7_4727

Product

Feature Type CDS
Coding Frame 1
Product Name
2-methylcitrate dehydratase
Synonyms
Evidence for Translation
Charge (pH 7) -3.90
Kyte-Doolittle Hydrophobicity Value -0.140
Molecular Weight (kDa) 54848.1
Isoelectric Point (pI) 6.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6S62 ISOMERASE 07/02/19 Crystal structure of 2-methylcitrate dehydratase (PrpD) from Pseudomonas aeruginosa in apo form. Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.36 X-RAY DIFFRACTION 99.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 150 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000765 (441 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_4727
Search term: prpD

Human Homologs

References

No references are associated with this feature.