Pseudomonas aeruginosa PA7, PSPA7_5394 (hitA)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PA7 GCF_000017205.1|latest
Locus Tag	PSPA7_5394
Name	hitA
Replicon	chromosome
Genomic location	5559832 - 5560839 (+ strand)

Cross-References

RefSeq	YP_001350724.1
GI	152988703
Entrez	5354124
INSDC	ABR85886.1
NCBI Locus Tag	PSPA7_5394
UniParc	UPI0000D73913
UniProtKB Acc	A6VCD9
UniProtKB ID	A6VCD9_PSEA7
UniRef100	UniRef100_A6VCD9
UniRef50	UniRef50_V6JBE1
UniRef90	UniRef90_A6VCD9

Product

Feature Type	CDS
Coding Frame	1
Product Name	ferric iron-binding periplasmic protein HitA
Synonyms
Evidence for Translation
Charge (pH 7)	-5.82
Kyte-Doolittle Hydrophobicity Value	-0.248
Molecular Weight (kDa)	36264.9
Isoelectric Point (pI)	5.28

Subcellular localization

Individual Mappings	Localization Confidence PMID Periplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
6J2S	METAL BINDING PROTEIN	01/02/19	Structure of HitA bound to gallium from Pseudomonas aeruginosa	Pseudomonas aeruginosa	1.73005	X-RAY DIFFRACTION	99.3
6IVY	STRUCTURAL PROTEIN	12/04/18	Crystal structure of iron-bound HitA from Pseudomonas aeruginosa	Pseudomonas aeruginosa PAO1	2	X-RAY DIFFRACTION	99.3
6IWF	METAL BINDING PROTEIN	12/05/18	Crystal structure of HitA from Pseudomonas aeruginosa	Pseudomonas aeruginosa PAO1	1.70662	X-RAY DIFFRACTION	99.4

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 313 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG004337 (456 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSPA7_5394 Search term: hitA Search term: ferric iron-binding periplasmic protein HitA

Human Homologs

References