Pseudomonas aeruginosa PA7, PSPA7_5468 (tpiA)

Gene Feature Overview

Strain	Pseudomonas aeruginosa PA7 GCF_000017205.1|latest
Locus Tag	PSPA7_5468
Name	tpiA
Replicon	chromosome
Genomic location	5634801 - 5635556 (- strand)

Cross-References

RefSeq	YP_001350790.1
GI	152986269
EC Number	5.3.1.1
Entrez	5354999
INSDC	ABR83452.1
NCBI Locus Tag	PSPA7_5468
UniParc	UPI000157777E
UniProtKB Acc	A6VCK5
UniProtKB ID	TPIS_PSEA7
UniRef100	UniRef100_A6VCK5
UniRef50	UniRef50_P50921
UniRef90	UniRef90_A6VCK5

Product

Feature Type	CDS
Coding Frame	1
Product Name	triosephosphate isomerase
Synonyms
Evidence for Translation
Charge (pH 7)	-3.19
Kyte-Doolittle Hydrophobicity Value	0.327
Molecular Weight (kDa)	25.5
Isoelectric Point (pI)	5.69

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 612 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG004393 (536 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSPA7_5468 Search term: tpiA Search term: triosephosphate isomerase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000229270 triosephosphate isomerase 1 [Source:HGNC Symbol;Acc:HGNC:12009] E-value: 7.8e-46 Percent Identity: 45.8
Ensembl 110, assembly GRCh38.p14	ENSP00000484435 triosephosphate isomerase 1 [Source:HGNC Symbol;Acc:HGNC:12009] E-value: 7.8e-46 Percent Identity: 45.8
Ensembl 110, assembly GRCh38.p14	ENSP00000379933 triosephosphate isomerase 1 [Source:HGNC Symbol;Acc:HGNC:12009] E-value: 7.8e-46 Percent Identity: 45.8

References