Pseudomonas aeruginosa PA7, PSPA7_5568 (accC2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa PA7
GCF_000017205.1|latest
Locus Tag
PSPA7_5568
Name
accC2
Replicon chromosome
Genomic location 5735353 - 5736702 (+ strand)

Cross-References

RefSeq YP_001350889.1
GI 152986858
EC Number 6.4.1.2
Entrez 5357806
INSDC ABR84041.1
NCBI Locus Tag PSPA7_5568
UniParc UPI00001251AF
UniProtKB Acc A6VCV4
UniProtKB ID A6VCV4_PSEA7
UniRef100 UniRef100_P37798
UniRef50 UniRef50_P37798
UniRef90 UniRef90_P37798

Product

Feature Type CDS
Coding Frame 1
Product Name
acetyl-CoA carboxylase biotin carboxylase subunit
Synonyms
Evidence for Translation
Charge (pH 7) -5.82
Kyte-Doolittle Hydrophobicity Value -0.183
Molecular Weight (kDa) 48.9
Isoelectric Point (pI) 6.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2VQD LIGASE 03/13/08 Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa complexed with AMPCP PSEUDOMONAS AERUGINOSA 2.41 X-RAY DIFFRACTION 100.0
2C00 LIGASE 03/21/08 Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa in apo form PSEUDOMONAS AERUGINOSA 2.5 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 630 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004477 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPA7_5568
Search term: accC2

Human Homologs

Ensembl 110, assembly GRCh38.p14
propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653]
E-value: 5.0e-120
Percent Identity: 47.5
Ensembl 110, assembly GRCh38.p14
propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653]
E-value: 5.0e-120
Percent Identity: 47.5
Ensembl 110, assembly GRCh38.p14
propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653]
E-value: 5.0e-120
Percent Identity: 47.5

References

No references are associated with this feature.