Pseudomonas syringae pv. tomato DC3000, PSPTO_2159

Gene Feature Overview

Strain	Pseudomonas syringae pv. tomato DC3000 (Buell et al., 2003) GCF_000007805.1|latest
Locus Tag	PSPTO_2159
NCBI Old Locus Tag	PSPTO2159
Name	Synonym: PSPTO2159
Replicon	chromosome
Genomic location	2370963 - 2372933 (- strand)

Cross-References

RefSeq	NP_791981.1
GI	28869362
Entrez	1183806
INSDC	AAO55676.1
NCBI Locus Tag	PSPTO_2159
NCBI Old Locus Tag	PSPTO2159
UniParc	UPI0000008AA6
UniProtKB Acc	Q884D4
UniProtKB ID	MACB1_PSESM
UniRef100	UniRef100_Q884D4
UniRef50	UniRef50_Q4K9A4
UniRef90	UniRef90_Q48KB2

Product

Feature Type	CDS
Coding Frame	1
Product Name	macrolide ABC efflux protein
Synonyms
Evidence for Translation
Charge (pH 7)	0.09
Kyte-Doolittle Hydrophobicity Value	0.153
Molecular Weight (kDa)	69.6
Isoelectric Point (pI)	7.02

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG003137 (481 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSPTO_2159 Search term: macrolide ABC efflux protein

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000392983 ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45] E-value: 1.7e-20 Percent Identity: 33.7
Ensembl 110, assembly GRCh38.p14	ENSP00000496956 ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45] E-value: 1.7e-20 Percent Identity: 33.7
Ensembl 110, assembly GRCh38.p14	ENSP00000265723 ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45] E-value: 1.7e-20 Percent Identity: 33.7
Ensembl 110, assembly GRCh38.p14	ENSP00000352135 ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45] E-value: 1.7e-20 Percent Identity: 33.7

References