Pseudomonas savastanoi pv. phaseolicola 1448A, PSPPH_2272 (mexF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas savastanoi pv. phaseolicola 1448A
GCF_000012205.1|latest
Locus Tag
PSPPH_2272
Name
mexF
Replicon chromosome
Genomic location 2634958 - 2638149 (- strand)

Cross-References

RefSeq YP_274481.1
GI 71736728
Entrez 3559113
INSDC AAZ36492.1
NCBI Locus Tag PSPPH_2272
UniParc UPI00005757FC
UniProtKB Acc Q48JE7
UniProtKB ID Q48JE7_PSE14
UniRef100 UniRef100_Q48JE7
UniRef50 UniRef50_Q880Q4
UniRef90 UniRef90_Q880Q4

Product

Feature Type CDS
Coding Frame 1
Product Name
multidrug efflux RND transporter MexF
Synonyms
Evidence for Translation
Charge (pH 7) -10.67
Kyte-Doolittle Hydrophobicity Value 0.318
Molecular Weight (kDa) 115242.5
Isoelectric Point (pI) 5.41

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
adeF AdeF is the membrane fusion protein of the multidrug efflux complex AdeFGH. [PMID:20696879] ARO:3000777 protein homolog model Strict 1337.4 66.19 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 489 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000417 (2093 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PSPPH_2272
Search term: mexF

Human Homologs

References

No references are associated with this feature.