Pseudomonas savastanoi pv. phaseolicola 1448A, PSPPH_2433

Gene Feature Overview

Strain	Pseudomonas savastanoi pv. phaseolicola 1448A GCF_000012205.1|latest
Locus Tag	PSPPH_2433
Name
Replicon	chromosome
Genomic location	2814315 - 2815145 (+ strand)

Cross-References

RefSeq	YP_274631.1
GI	71733406
EC Number	4.2.1.17
Entrez	3555690
INSDC	AAZ33170.1
NCBI Locus Tag	PSPPH_2433
UniParc	UPI0000575890
UniProtKB Acc	Q48J00
UniProtKB ID	Q48J00_PSE14
UniRef100	UniRef100_Q48J00
UniRef50	UniRef50_O69762
UniRef90	UniRef90_O69762

Product

Feature Type	CDS
Coding Frame	1
Product Name	p-hydroxycinnamoyl CoA hydratase/lyase
Synonyms
Evidence for Translation
Charge (pH 7)	-2.63
Kyte-Doolittle Hydrophobicity Value	-0.350
Molecular Weight (kDa)	31.1
Isoelectric Point (pI)	5.54

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
2VSS	LYASE	04/29/08	Wild-type Hydroxycinnamoyl-CoA hydratase lyase in complex with acetyl- CoA and vanillin	PSEUDOMONAS FLUORESCENS	2.22	X-RAY DIFFRACTION	94.9
2J5I	LYASE	09/18/06	Crystal Structure of Hydroxycinnamoyl-CoA Hydratase-Lyase	PSEUDOMONAS FLUORESCENS	1.8	X-RAY DIFFRACTION	94.9
2VSU	LYASE	04/29/08	A ternary complex of Hydroxycinnamoyl-CoA Hydratase-Lyase (HCHL) with acetyl-Coenzyme A and vanillin gives insights into substrate specificity and mechanism.	PSEUDOMONAS FLUORESCENS	1.9	X-RAY DIFFRACTION	94.6
6L3O	LYASE	10/12/19	Crystal strcuture of Feruloyl-CoA hydratase lyase(FCHL) from Pseudomonas putida KT2440	Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)	1.65	X-RAY DIFFRACTION	92.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 495 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG016253 (84 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PSPPH_2433 Search term: p-hydroxycinnamoyl CoA hydratase/lyase

Human Homologs

References