Pseudomonas sp. UW4, PputUW4_00070 (polA)

Gene Feature Overview

Strain	Pseudomonas sp. UW4 GCF_000316175.1|latest
Locus Tag	PputUW4_00070
Name	polA
Replicon	chromosome
Genomic location	70409 - 73213 (+ strand)

Cross-References

RefSeq	YP_007027084.1
GI	426406985
EC Number	2.7.7.7
Entrez	14053757
NCBI Locus Tag	PputUW4_00070

Product

Feature Type	CDS
Coding Frame	1
Product Name	DNA polymerase I
Synonyms
Evidence for Translation
Charge (pH 7)	-28.90
Kyte-Doolittle Hydrophobicity Value	-0.137
Molecular Weight (kDa)	102004.3
Isoelectric Point (pI)	4.84

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 591 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG005032 (536 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PputUW4_00070 Search term: polA Search term: DNA polymerase I

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000435506 DNA polymerase nu [Source:HGNC Symbol;Acc:HGNC:18870] E-value: 7.2e-52 Percent Identity: 29.8
Ensembl 110, assembly GRCh38.p14	ENSP00000372316 DNA polymerase nu [Source:HGNC Symbol;Acc:HGNC:18870] E-value: 7.2e-52 Percent Identity: 29.8

References