Pseudomonas sp. UW4, PputUW4_03799 (lpdA2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas sp. UW4
GCF_000316175.1|latest
Locus Tag
PputUW4_03799
Name
lpdA2
Replicon chromosome
Genomic location 4391949 - 4393385 (- strand)

Cross-References

RefSeq YP_007030796.1
GI 426410697
EC Number 1.8.1.4
Entrez 14054722
NCBI Locus Tag PputUW4_03799

Product

Feature Type CDS
Coding Frame 1
Product Name
dihydrolipoyl dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -6.01
Kyte-Doolittle Hydrophobicity Value 0.171
Molecular Weight (kDa) 49809.0
Isoelectric Point (pI) 6.20

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5TR3 HYDROLASE 10/25/16 2.5 Angstrom Resolution Crystal Structure of Dihydrolipoyl Dehydrogenase from Pseudomonas putida in Complex with FAD. Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440) 2.5 X-RAY DIFFRACTION 90.8
6AWA OXIDOREDUCTASE 09/05/17 1.83 Angstrom Resolution Crystal Structure of Dihydrolipoyl Dehydrogenase from Pseudomonas putida in Complex with FAD and Adenosine-5'-monophosphate. Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440) 1.83 X-RAY DIFFRACTION 90.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 642 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003776 (538 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PputUW4_03799
Search term: lpdA2

Human Homologs

Ensembl 110, assembly GRCh38.p14
dihydrolipoamide dehydrogenase [Source:HGNC Symbol;Acc:HGNC:2898]
E-value: 3.5e-119
Percent Identity: 48.3
Ensembl 110, assembly GRCh38.p14
dihydrolipoamide dehydrogenase [Source:HGNC Symbol;Acc:HGNC:2898]
E-value: 3.5e-119
Percent Identity: 48.3

References

No references are associated with this feature.