Pseudomonas sp. UW4, PputUW4_04336 (pyk2)

Gene Feature Overview

Strain	Pseudomonas sp. UW4 GCF_000316175.1|latest
Locus Tag	PputUW4_04336
Name	pyk2
Replicon	chromosome
Genomic location	4976184 - 4977635 (+ strand)

Cross-References

RefSeq	YP_007031333.1
GI	426411234
EC Number	2.7.1.40
Entrez	14051749
INSDC	AFY21528.1
NCBI Locus Tag	PputUW4_04336
UniParc	UPI00026FD872
UniProtKB Acc	K9NQS7
UniProtKB ID	K9NQS7_9PSED
UniRef100	UniRef100_K9NQS7
UniRef50	UniRef50_Q4K7A5
UniRef90	UniRef90_Q4K7A5

Product

Feature Type	CDS
Coding Frame	1
Product Name	pyruvate kinase
Synonyms
Evidence for Translation
Charge (pH 7)	-2.97
Kyte-Doolittle Hydrophobicity Value	-0.108
Molecular Weight (kDa)	52.1
Isoelectric Point (pI)	6.58

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 614 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG003926 (537 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PputUW4_04336 Search term: pyk2 Search term: pyruvate kinase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000320171 pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] E-value: 4.1e-67 Percent Identity: 36.5
Ensembl 110, assembly GRCh38.p14	ENSP00000456970 pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] E-value: 4.1e-67 Percent Identity: 36.5
Ensembl 110, assembly GRCh38.p14	ENSP00000455901 pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] E-value: 4.1e-67 Percent Identity: 36.5
Ensembl 110, assembly GRCh38.p14	ENSP00000455736 pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] E-value: 4.1e-67 Percent Identity: 36.5

References