Pseudomonas protegens Pf-5, PFL_0358 (mutY)

Gene Feature Overview

Strain	Pseudomonas protegens Pf-5 GCF_000012265.1|latest
Locus Tag	PFL_0358
Name	mutY
Replicon	chromosome
Genomic location	409444 - 410511 (- strand)

Cross-References

RefSeq	YP_257502.1
GI	70733862
EC Number	3.2.2.-
Entrez	3480949
INSDC	AAY95767.1
NCBI Locus Tag	PFL_0358
UniParc	UPI000054CCBB
UniProtKB Acc	Q4KJT1
UniProtKB ID	Q4KJT1_PSEF5
UniRef100	UniRef100_Q4KJT1
UniRef50	UniRef50_P44320
UniRef90	UniRef90_Q4KJT1

Product

Feature Type	CDS
Coding Frame	1
Product Name	A/G-specific adenine glycosylase
Synonyms
Evidence for Translation
Charge (pH 7)	0.53
Kyte-Doolittle Hydrophobicity Value	-0.222
Molecular Weight (kDa)	39866.6
Isoelectric Point (pI)	7.11

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 623 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG004741 (533 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PFL_0358 Search term: mutY Search term: A/G-specific adenine glycosylase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000407590 mutY DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7527] E-value: 1.3e-54 Percent Identity: 37.0
Ensembl 110, assembly GRCh38.p14	ENSP00000346354 mutY DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7527] E-value: 1.3e-54 Percent Identity: 37.0
Ensembl 110, assembly GRCh38.p14	ENSP00000361176 mutY DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7527] E-value: 1.3e-54 Percent Identity: 37.0
Ensembl 110, assembly GRCh38.p14	ENSP00000361182 mutY DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7527] E-value: 1.3e-54 Percent Identity: 37.0
Ensembl 110, assembly GRCh38.p14	ENSP00000436469 mutY DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7527] E-value: 1.3e-54 Percent Identity: 37.0
Ensembl 110, assembly GRCh38.p14	ENSP00000403655 mutY DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7527] E-value: 1.3e-54 Percent Identity: 37.0
Ensembl 110, assembly GRCh38.p14	ENSP00000518552 mutY DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7527] E-value: 1.3e-54 Percent Identity: 37.0
Ensembl 110, assembly GRCh38.p14	ENSP00000500828 mutY DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7527] E-value: 1.3e-54 Percent Identity: 37.0
Ensembl 110, assembly GRCh38.p14	ENSP00000499896 novel protein E-value: 1.3e-54 Percent Identity: 37.0
Ensembl 110, assembly GRCh38.p14	ENSP00000433130 mutY DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7527] E-value: 1.3e-54 Percent Identity: 37.0
Ensembl 110, assembly GRCh38.p14	ENSP00000361187 mutY DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7527] E-value: 1.3e-54 Percent Identity: 37.0
Ensembl 110, assembly GRCh38.p14	ENSP00000500891 mutY DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7527] E-value: 1.3e-54 Percent Identity: 37.0
Ensembl 110, assembly GRCh38.p14	ENSP00000347685 mutY DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7527] E-value: 1.3e-54 Percent Identity: 37.0
Ensembl 110, assembly GRCh38.p14	ENSP00000431264 mutY DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7527] E-value: 1.3e-54 Percent Identity: 37.0
Ensembl 110, assembly GRCh38.p14	ENSP00000409718 mutY DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7527] E-value: 1.3e-54 Percent Identity: 37.0
Ensembl 110, assembly GRCh38.p14	ENSP00000361170 mutY DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7527] E-value: 1.3e-54 Percent Identity: 37.0

References