Pseudomonas protegens Pf-5, PFL_1412

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas protegens Pf-5
GCF_000012265.1|latest
Locus Tag
PFL_1412
Name
Replicon chromosome
Genomic location 1590850 - 1591782 (- strand)

Cross-References

RefSeq YP_258541.1
GI 70728792
Entrez 3478954
INSDC AAY90697.1
NCBI Locus Tag PFL_1412
UniParc UPI000054D0C7
UniProtKB Acc Q4KGU2
UniProtKB ID 4HYPE_PSEF5
UniRef100 UniRef100_Q4KGU2
UniRef50 UniRef50_Q9I476
UniRef90 UniRef90_Q4KGU2

Product

Feature Type CDS
Coding Frame 1
Product Name
proline racemase
Synonyms
Evidence for Translation
Charge (pH 7) -6.09
Kyte-Doolittle Hydrophobicity Value -0.109
Molecular Weight (kDa) 33441.5
Isoelectric Point (pI) 6.18

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4J9W Isomerase/Isomerase Inhibitor complex 02/17/13 Crystal structure of the complex of a hydroxyproline epimerase (TARGET EFI-506499, PSEUDOMONAS FLUORESCENS PF-5) with the inhibitor pyrrole-2-carboxylate Pseudomonas protegens 1.6 X-RAY DIFFRACTION 100.0
4J9X ISOMERASE 02/17/13 Crystal structure of the complex of a hydroxyproline epimerase (TARGET EFI-506499, PSEUDOMONAS FLUORESCENS PF-5) with trans-4-hydroxy-l-proline Pseudomonas protegens 1.7 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 153 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001206 (807 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PFL_1412
Search term: proline racemase

Human Homologs

Ensembl 110, assembly GRCh38.p14
trans-L-3-hydroxyproline dehydratase [Source:HGNC Symbol;Acc:HGNC:20488]
E-value: 2.0e-30
Percent Identity: 28.3

References

No references are associated with this feature.