Pseudomonas protegens Pf-5, PFL_1697 (pyk_1)

Gene Feature Overview

Strain	Pseudomonas protegens Pf-5 GCF_000012265.1|latest
Locus Tag	PFL_1697
Name	pyk_1
Replicon	chromosome
Genomic location	1897586 - 1899001 (- strand)

Cross-References

RefSeq	YP_258823.1
GI	70729087
EC Number	2.7.1.40
Entrez	3477883
INSDC	AAY90992.1
NCBI Locus Tag	PFL_1697
UniParc	UPI000054D1DE
UniProtKB Acc	Q4KG10
UniProtKB ID	Q4KG10_PSEF5
UniRef100	UniRef100_Q4KG10
UniRef50	UniRef50_Q44473
UniRef90	UniRef90_Q4KG10

Product

Feature Type	CDS
Coding Frame	1
Product Name	pyruvate kinase
Synonyms
Evidence for Translation
Charge (pH 7)	-6.89
Kyte-Doolittle Hydrophobicity Value	-0.028
Molecular Weight (kDa)	50.9
Isoelectric Point (pI)	5.25

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 614 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG001412 (474 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PFL_1697 Search term: pyk_1 Search term: pyruvate kinase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000334983 pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] E-value: 1.5e-82 Percent Identity: 38.9
Ensembl 110, assembly GRCh38.p14	ENSP00000513903 pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021] E-value: 1.5e-82 Percent Identity: 38.9

References