Pseudomonas protegens Pf-5, PFL_1720 (lpdA_1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas protegens Pf-5
GCF_000012265.1|latest
Locus Tag
PFL_1720
Name
lpdA_1
Replicon chromosome
Genomic location 1926050 - 1927486 (+ strand)

Cross-References

RefSeq YP_258846.1
GI 70729110
EC Number 1.8.1.4
Entrez 3478180
INSDC AAY91015.1
NCBI Locus Tag PFL_1720
UniParc UPI000054D1F5
UniProtKB Acc Q4KFY7
UniProtKB ID Q4KFY7_PSEF5
UniRef100 UniRef100_Q4KFY7
UniRef50 UniRef50_P31052
UniRef90 UniRef90_Q4KFY7

Product

Feature Type CDS
Coding Frame 1
Product Name
dihydrolipoamide dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -5.01
Kyte-Doolittle Hydrophobicity Value 0.175
Molecular Weight (kDa) 49.9
Isoelectric Point (pI) 6.33

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5TR3 HYDROLASE 10/25/16 2.5 Angstrom Resolution Crystal Structure of Dihydrolipoyl Dehydrogenase from Pseudomonas putida in Complex with FAD. Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440) 2.5 X-RAY DIFFRACTION 90.8
6AWA OXIDOREDUCTASE 09/05/17 1.83 Angstrom Resolution Crystal Structure of Dihydrolipoyl Dehydrogenase from Pseudomonas putida in Complex with FAD and Adenosine-5'-monophosphate. Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440) 1.83 X-RAY DIFFRACTION 90.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 645 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003776 (538 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PFL_1720
Search term: lpdA_1

Human Homologs

Ensembl 110, assembly GRCh38.p14
dihydrolipoamide dehydrogenase [Source:HGNC Symbol;Acc:HGNC:2898]
E-value: 5.9e-119
Percent Identity: 49.1
Ensembl 110, assembly GRCh38.p14
dihydrolipoamide dehydrogenase [Source:HGNC Symbol;Acc:HGNC:2898]
E-value: 5.9e-119
Percent Identity: 49.1

References

No references are associated with this feature.