Pseudomonas protegens Pf-5, PFL_4440 (purM)

Gene Feature Overview

Strain	Pseudomonas protegens Pf-5 GCF_000012265.1|latest
Locus Tag	PFL_4440
Name	purM
Replicon	chromosome
Genomic location	5149260 - 5150318 (+ strand)

Cross-References

RefSeq	YP_261528.1
GI	70731786
EC Number	6.3.3.1
Entrez	3478559
INSDC	AAY93691.1
NCBI Locus Tag	PFL_4440
UniParc	UPI000054DC46
UniProtKB Acc	Q4K8A5
UniProtKB ID	PUR5_PSEF5
UniRef100	UniRef100_Q4K8A5
UniRef50	UniRef50_Q8XAC5
UniRef90	UniRef90_Q4K8A5

Product

Feature Type	CDS
Coding Frame	1
Product Name	phosphoribosylaminoimidazole synthetase
Synonyms
Evidence for Translation
Charge (pH 7)	-11.79
Kyte-Doolittle Hydrophobicity Value	0.146
Molecular Weight (kDa)	36.9
Isoelectric Point (pI)	4.73

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 605 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000911 (537 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PFL_4440 Search term: purM Search term: phosphoribosylaminoimidazole synthetase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000371253 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163] E-value: 2.0e-95 Percent Identity: 50.7
Ensembl 110, assembly GRCh38.p14	ENSP00000371236 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163] E-value: 2.0e-95 Percent Identity: 50.7
Ensembl 110, assembly GRCh38.p14	ENSP00000371261 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163] E-value: 2.0e-95 Percent Identity: 50.7

References