Pseudomonas protegens Pf-5, PFL_4923 (lon_2)

Gene Feature Overview

Strain	Pseudomonas protegens Pf-5 GCF_000012265.1|latest
Locus Tag	PFL_4923
Name	lon_2
Replicon	chromosome
Genomic location	5672609 - 5675029 (+ strand)

Cross-References

RefSeq	YP_262003.1
GI	70732247
EC Number	3.4.21.53
Entrez	3479334
INSDC	AAY94152.1
NCBI Locus Tag	PFL_4923
UniParc	UPI000054DE1E
UniProtKB Acc	Q4K6Y0
UniProtKB ID	Q4K6Y0_PSEF5
UniRef100	UniRef100_Q4K6Y0
UniRef50	UniRef50_Q6ME13
UniRef90	UniRef90_Q4K6Y0

Product

Feature Type	CDS
Coding Frame	1
Product Name	endopeptidase La
Synonyms
Evidence for Translation
Charge (pH 7)	-8.50
Kyte-Doolittle Hydrophobicity Value	-0.326
Molecular Weight (kDa)	89.8
Isoelectric Point (pI)	6.43

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 542 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG000753 (534 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PFL_4923 Search term: lon_2 Search term: endopeptidase La

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000465585 lon peptidase 1, mitochondrial [Source:HGNC Symbol;Acc:HGNC:9479] E-value: 1.7e-182 Percent Identity: 46.9
Ensembl 110, assembly GRCh38.p14	ENSP00000353826 lon peptidase 1, mitochondrial [Source:HGNC Symbol;Acc:HGNC:9479] E-value: 1.7e-182 Percent Identity: 46.9
Ensembl 110, assembly GRCh38.p14	ENSP00000441523 lon peptidase 1, mitochondrial [Source:HGNC Symbol;Acc:HGNC:9479] E-value: 1.7e-182 Percent Identity: 46.9
Ensembl 110, assembly GRCh38.p14	ENSP00000468541 lon peptidase 1, mitochondrial [Source:HGNC Symbol;Acc:HGNC:9479] E-value: 1.7e-182 Percent Identity: 46.9

References